C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: troponin C, cardiac/slow skeletal
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000091898 Tnnc1 10090 + 14:31208312-31211729 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000161399 Tnnc1-002 31208332-31210998 retained_intron
  ENSMUST00000169169 Tnnc1-001 31208312-31211729 protein_coding
  ENSMUST00000170268 Tnnc1-003 31208330-31211636 nonsense_mediated_decay

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000161399ENSMUST00000169169ENSMUST00000170268
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000161399 N/A N/A 0.618±0.07 N/A 0.363±0.00 N/A N/A 0.171±0.03 N/A N/A N/A 0.732±0.30 0.396±0.00 0.285±0.16
ENSMUST00000169169 0.192±0.08 0.289±0.17 1.031±0.02 6.277±6.01 1.519±0.05 0.423±0.09 2506.205±373.29 3.112±2.02 14.141±10.65 20.678±1.42 206.960±130.69 0.924±0.37 18.263±18.71 0.397±0.23
ENSMUST00000170268 N/A N/A N/A 4.767±0.00 N/A N/A N/A 0.161±0.00 0.169±0.05 N/A N/A 0.995±0.51 16.000±14.86 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WP CIL_0007WP_0002 VISTA 14:30932335-31535522
CIL_00002S CIL_00002S_0002 CGP 14:31139013-31216946

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002086 IEA diaphragm contraction
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0005861 IEA troponin complex
GO:0006937 IEA regulation of muscle contraction
GO:0010038 IEA response to metal ion
GO:0015629 IEA actin cytoskeleton
GO:0031013 IEA troponin I binding
GO:0031014 IEA troponin T binding
GO:0032972 IMP regulation of muscle filament sliding speed
GO:0042803 IEA protein homodimerization activity
GO:0043292 IEA contractile fiber
GO:0043462 IDA regulation of ATPase activity
GO:0048306 IEA calcium-dependent protein binding
GO:0051015 IDA actin filament binding
GO:0055010 IEA ventricular cardiac muscle tissue morphogenesis
GO:0060048 IEA cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011400 tnnc1a troponin C type 1a (slow) protein_coding Danio_rerio
ENSDARG00000037539 tnnc1b troponin C type 1b (slow) protein_coding Danio_rerio
ENSG00000114854 TNNC1 troponin C type 1 (slow) protein_coding Homo_sapiens

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