C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: troponin C type 1 (slow)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000232975 TNNC1-001 ENSG00000114854 9606 - 3:52451102-52454070 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000232975
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000232975 0.851±0.00 2.000±0.00 0.873±0.00 0.270±0.00 45.922±42.76 0.896±0.43 1585.332±757.49 7.682±0.00 1.648±1.48 24.471±10.14 1848.449±922.71 2.328±1.36 15.990±9.48 37.685±33.99

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WP CIL_0007WP_0001 VISTA 3:52127966-52731115

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002086 IEA diaphragm contraction
GO:0005509 IDA:IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005739 IDA mitochondrion
GO:0005829 TAS cytosol
GO:0005861 IDA troponin complex
GO:0006937 IDA regulation of muscle contraction
GO:0010038 IEA response to metal ion
GO:0015629 IDA actin cytoskeleton
GO:0030049 TAS muscle filament sliding
GO:0031013 IPI troponin I binding
GO:0031014 IPI troponin T binding
GO:0032972 ISS regulation of muscle filament sliding speed
GO:0042803 IDA protein homodimerization activity
GO:0043292 IEA contractile fiber
GO:0043462 ISS regulation of ATPase activity
GO:0048306 IPI calcium-dependent protein binding
GO:0051015 ISS actin filament binding
GO:0055010 IMP ventricular cardiac muscle tissue morphogenesis
GO:0060048 IMP cardiac muscle contraction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000169169 Tnnc1-001 protein_coding Mus_musculus 0 706
ENSMUST00000170268 Tnnc1-003 nonsense_mediated_decay Mus_musculus 0 547
ENSMUST00000161399 Tnnc1-002 retained_intron Mus_musculus 0 464

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