C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal peptidase complex subunit 1 homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114902 SPCS1 9606 + 3:52704955-52711146 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233025 SPCS1-201 52705841-52708179 protein_coding
  ENST00000423431 SPCS1-004 52704955-52708157 protein_coding
  ENST00000448693 SPCS1-002 52706109-52707384 retained_intron
  ENST00000474945 SPCS1-003 52706143-52708019 retained_intron
  ENST00000602728 SPCS1-006 52706078-52708166 protein_coding
  ENST00000619898 SPCS1-001 52705636-52711146 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000474945ENST00000602728
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000474945 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 92.971±0.00 N/A
ENST00000602728 53.757±0.00 74.561±0.00 31.479±0.00 71.129±13.08 46.367±6.31 43.181±11.23 28.921±12.50 94.525±6.54 57.869±34.44 39.195±15.58 53.255±36.48 84.179±36.25 102.520±5.69 124.944±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WP CIL_0007WP_0001 VISTA 3:52127966-52731115
CIL_0003R6 CIL_0003R6_0002 CGP 3:52681156-52706083
CIL_0007GX CIL_0007GX_0002 CGP 3:52694485-52711146
CIL_0007H1 CIL_0007H1_0002 CGP 3:52704955-52770949

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005515 IPI protein binding
GO:0005787 IEA:TAS signal peptidase complex
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006412 TAS translation
GO:0006465 IEA signal peptide processing
GO:0006508 IEA:TAS proteolysis
GO:0006614 TAS SRP-dependent cotranslational protein targeting to membrane
GO:0008233 IEA peptidase activity
GO:0010467 TAS gene expression
GO:0016021 IEA integral component of membrane
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0043022 IEA ribosome binding
GO:0044267 TAS cellular protein metabolic process
GO:0050796 TAS regulation of insulin secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059298 spcs1 signal peptidase complex subunit 1 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000021917 Spcs1 signal peptidase complex subunit 1 homolog (S. cerevisiae) protein_coding Mus_musculus

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