C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenomatosis polyposis coli 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000115266 APC2 9606 + 19:1446302-1473244 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000233607 APC2-201 1450149-1473244 protein_coding
  ENST00000238483 APC2-006 1452800-1465496 protein_coding
  ENST00000535453 APC2-004 1451289-1473244 protein_coding
  ENST00000587149 APC2-008 1452198-1453614 protein_coding
  ENST00000587869 APC2-005 1446302-1455245 protein_coding
  ENST00000590469 APC2-001 1450149-1465409 protein_coding
  ENST00000590877 APC2-007 1450149-1455445 protein_coding
  ENST00000593146 APC2-003 1450295-1465418 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonHeartLungENST00000233607
Transcript ID Bladder Brain Colon Heart Lung
ENST00000233607 0.034±0.00 8.983±0.00 0.413±0.35 0.029±0.00 0.070±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ZF CIL_0000ZF_0001 CGP 19:1438358-1473244
CIL_0000ZG CIL_0000ZG_0001 CGP 19:1446302-1479556

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005881 IDA cytoplasmic microtubule
GO:0005884 IDA actin filament
GO:0008013 IEA:IDA beta-catenin binding
GO:0008017 IEA microtubule binding
GO:0015630 IDA microtubule cytoskeleton
GO:0016055 IEA Wnt signaling pathway
GO:0016342 IDA catenin complex
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0031258 IDA lamellipodium membrane
GO:0035414 IDA negative regulation of catenin import into nucleus
GO:0048471 IDA perinuclear region of cytoplasm
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063007 apc2 adenomatosis polyposis coli 2 protein_coding Danio_rerio
ENSMUSG00000020135 Apc2 adenomatosis polyposis coli 2 protein_coding Mus_musculus

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