C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adenomatosis polyposis coli 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000233607 APC2-201 ENSG00000115266 9606 + 19:1450149-1473244 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonHeartLungENST00000233607
Transcript ID Bladder Brain Colon Heart Lung
ENST00000233607 0.034±0.00 8.983±0.00 0.413±0.35 0.029±0.00 0.070±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ZF CIL_0000ZF_0001 CGP 19:1438358-1473244
CIL_0000ZG CIL_0000ZG_0001 CGP 19:1446302-1479556

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0005881 IDA cytoplasmic microtubule
GO:0005884 IDA actin filament
GO:0008013 IEA:IDA beta-catenin binding
GO:0008017 IEA microtubule binding
GO:0015630 IDA microtubule cytoskeleton
GO:0016055 IEA Wnt signaling pathway
GO:0016342 IDA catenin complex
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0031258 IDA lamellipodium membrane
GO:0035414 IDA negative regulation of catenin import into nucleus
GO:0048471 IDA perinuclear region of cytoplasm
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105359 Apc2-001 protein_coding Mus_musculus 0 4229
ENSMUST00000020349 Apc2-201 protein_coding Mus_musculus 0 4178
ENSMUST00000138909 Apc2-004 protein_coding Mus_musculus 0 318
ENSMUST00000140658 Apc2-005 retained_intron Mus_musculus 0 204
ENSDART00000149956 apc-001 protein_coding Danio_rerio 1.4013e-45 191
ENSDART00000044432 apc-201 protein_coding Danio_rerio 5.60519e-45 189

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