C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adenomatosis polyposis coli 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020135 Apc2 10090 + 10:80295977-80318263 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020349 Apc2-201 80301820-80318256 protein_coding
  ENSMUST00000105359 Apc2-001 80295977-80318263 protein_coding
  ENSMUST00000138909 Apc2-004 80301035-80302406 protein_coding
  ENSMUST00000140658 Apc2-005 80300847-80303355 retained_intron
  ENSMUST00000140828 Apc2-003 80301034-80302347 protein_coding
  ENSMUST00000154212 Apc2-002 80299091-80302361 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENSMUST00000020349ENSMUST00000105359
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENSMUST00000020349 N/A 0.837±0.00 N/A N/A N/A 0.784±0.05 0.381±0.00 N/A N/A 0.114±0.01 1.177±0.50 0.583±0.00 0.325±0.23
ENSMUST00000105359 0.774±0.23 1.117±0.39 0.848±0.00 39.915±17.31 0.703±0.06 0.799±0.02 0.611±0.22 0.388±0.05 1.063±0.35 0.122±0.00 1.150±0.28 0.842±0.62 0.258±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ZF CIL_0000ZF_0002 CGP 10:80292453-80318263
CIL_0000ZG CIL_0000ZG_0002 CGP 10:80295977-80320537

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005881 IEA cytoplasmic microtubule
GO:0005884 IEA actin filament
GO:0008013 IEA beta-catenin binding
GO:0008017 IEA microtubule binding
GO:0015630 IEA microtubule cytoskeleton
GO:0016055 IEA Wnt signaling pathway
GO:0016342 IEA catenin complex
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0031258 IEA lamellipodium membrane
GO:0035414 IEA negative regulation of catenin import into nucleus
GO:0048471 IEA perinuclear region of cytoplasm
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063007 apc2 adenomatosis polyposis coli 2 protein_coding Danio_rerio
ENSG00000115266 APC2 adenomatosis polyposis coli 2 protein_coding Homo_sapiens

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