C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spermidine synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000116649 SRM 9606 - 1:11054584-11060024 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376957 SRM-001 11054589-11060024 protein_coding
  ENST00000459997 SRM-005 11056011-11060020 nonsense_mediated_decay
  ENST00000465788 SRM-006 11056011-11058873 protein_coding
  ENST00000475189 SRM-002 11054584-11055204 retained_intron
  ENST00000487300 SRM-007 11056702-11059686 protein_coding
  ENST00000490101 SRM-004 11054664-11055820 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376957ENST00000475189ENST00000487300ENST00000490101
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376957 40.006±0.00 80.146±0.00 1.320±0.00 20.190±16.32 22.978±21.49 22.480±21.74 19.309±0.00 20.691±18.45 20.611±19.42 14.343±12.91 31.298±26.63 48.242±32.14 39.713±19.54 38.788±29.06
ENST00000475189 N/A N/A N/A N/A 1.898±0.00 N/A N/A N/A N/A N/A N/A 2.294±0.00 7.838±0.00 3.508±0.00
ENST00000487300 N/A N/A N/A N/A N/A N/A N/A N/A 0.393±0.00 N/A N/A N/A N/A N/A
ENST00000490101 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 24.263±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008RU CIL_0008RU_0001 VISTA 1:10491513-11092116
CIL_0008JG CIL_0008JG_0001 VISTA 1:10565145-11165671
CIL_0008JY CIL_0008JY_0001 VISTA 1:10605072-11206087

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004766 IDA spermidine synthase activity
GO:0005829 TAS cytosol
GO:0006595 TAS polyamine metabolic process
GO:0008152 IEA metabolic process
GO:0008295 IEA spermidine biosynthetic process
GO:0016740 IEA transferase activity
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042803 IDA protein homodimerization activity
GO:0044281 TAS small molecule metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055760 srm spermidine synthase protein_coding Danio_rerio
ENSMUSG00000006442 Srm spermidine synthase protein_coding Mus_musculus

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