C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 5B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000117139 KDM5B 9606 - 1:202724491-202809470 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000235790 KDM5B-002 202729905-202807299 protein_coding
  ENST00000367264 KDM5B-003 202727443-202808418 protein_coding
  ENST00000367265 KDM5B-001 202724491-202809470 protein_coding
  ENST00000456180 KDM5B-007 202753044-202758949 processed_transcript
  ENST00000467487 KDM5B-004 202774630-202807205 processed_transcript
  ENST00000470573 KDM5B-006 202773217-202806751 processed_transcript
  ENST00000472822 KDM5B-005 202729316-202736236 retained_intron
  ENST00000491153 KDM5B-009 202729901-202732141 retained_intron
  ENST00000498276 KDM5B-008 202745877-202746595 retained_intron
  ENST00000602511 KDM5B-010 202767031-202808125 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000235790ENST00000367264ENST00000367265
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000235790 N/A N/A 3.167±0.00 2.626±0.00 5.324±0.00 2.227±0.00 0.445±0.00 1.135±0.00 4.548±0.00 3.055±0.00 0.447±0.00 4.018±0.00 2.373±0.00 51.945±0.00
ENST00000367264 6.348±0.00 4.090±0.00 1.410±0.00 2.490±0.25 3.447±1.46 2.151±0.86 1.445±0.79 2.635±1.71 2.358±1.07 3.554±0.17 1.244±0.42 3.812±1.42 6.037±2.48 55.184±12.83
ENST00000367265 N/A N/A N/A 0.496±0.00 N/A 0.525±0.00 0.107±0.00 N/A N/A N/A 0.260±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IEA histone demethylase activity (H3-K4 specific)
GO:0034647 IDA histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 IDA histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 IDA histone H3-K4 demethylation
GO:0034721 IDA histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003098 kdm5bb lysine (K)-specific demethylase 5Bb protein_coding Danio_rerio
ENSDARG00000057093 kdm5ba lysine (K)-specific demethylase 5Ba protein_coding Danio_rerio
ENSMUSG00000042207 Kdm5b lysine (K)-specific demethylase 5B protein_coding Mus_musculus

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