C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 5B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000367264 KDM5B-003 ENSG00000117139 9606 - 1:202727443-202808418 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000367264
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000367264 6.348±0.00 4.090±0.00 1.410±0.00 2.490±0.25 3.447±1.46 2.151±0.86 1.445±0.79 2.635±1.71 2.358±1.07 3.554±0.17 1.244±0.42 3.812±1.42 6.037±2.48 55.184±12.83

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0034647 IDA histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 IDA histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 IDA histone H3-K4 demethylation
GO:0034721 IDA histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000047714 Kdm5b-001 protein_coding Mus_musculus 0 5408
ENSMUST00000112198 Kdm5b-003 protein_coding Mus_musculus 0 4553
ENSMUST00000112197 Kdm5b-002 retained_intron Mus_musculus 0 1212
ENSMUST00000133725 Kdm5b-004 retained_intron Mus_musculus 0 612
ENSMUST00000082177 Kdm5c-004 protein_coding Mus_musculus 0 420
ENSMUST00000112588 Kdm5c-001 protein_coding Mus_musculus 0 420
ENSMUST00000112584 Kdm5c-002 protein_coding Mus_musculus 0 420
ENSMUST00000186128 Kdm5b-005 retained_intron Mus_musculus 0 226

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