C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: lysine (K)-specific demethylase 5B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042207 Kdm5b 10090 + 1:134560171-134635285 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047714 Kdm5b-001 134560171-134635285 protein_coding
  ENSMUST00000112197 Kdm5b-002 134560207-134606791 retained_intron
  ENSMUST00000112198 Kdm5b-003 134560192-134631522 protein_coding
  ENSMUST00000133725 Kdm5b-004 134621880-134625101 retained_intron
  ENSMUST00000186128 Kdm5b-005 134587977-134590686 retained_intron
  ENSMUST00000191572 Kdm5b-006 134622800-134627201 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047714ENSMUST00000112197ENSMUST00000112198
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047714 2.916±0.89 1.554±0.07 5.219±1.07 5.621±3.15 2.017±0.43 2.556±0.33 0.656±0.19 2.009±0.17 1.339±0.54 2.670±0.36 0.483±0.15 4.101±0.93 2.636±1.55 8.436±3.65
ENSMUST00000112197 N/A 9.316±1.32 N/A N/A 5.814±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000112198 3.678±1.14 3.276±0.55 2.324±0.20 12.915±3.45 4.931±1.87 3.176±0.63 1.395±0.43 1.558±0.45 1.317±0.95 2.153±0.59 0.949±0.15 8.872±2.46 8.623±4.43 15.693±3.88

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IDA histone demethylase activity (H3-K4 specific)
GO:0034647 ISS histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 ISS histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 ISS histone H3-K4 demethylation
GO:0034721 IEA histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0042752 NAS regulation of circadian rhythm
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003098 kdm5bb lysine (K)-specific demethylase 5Bb protein_coding Danio_rerio
ENSDARG00000057093 kdm5ba lysine (K)-specific demethylase 5Ba protein_coding Danio_rerio
ENSG00000117139 KDM5B lysine (K)-specific demethylase 5B protein_coding Homo_sapiens

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