C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: lysine (K)-specific demethylase 5B
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000367265 KDM5B-001 ENSG00000117139 9606 - 1:202724491-202809470 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainColonHeartMuscleENST00000367265
Transcript ID Brain Colon Heart Muscle
ENST00000367265 0.496±0.00 0.525±0.00 0.107±0.00 0.260±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0032453 IEA histone demethylase activity (H3-K4 specific)
GO:0034647 IDA histone demethylase activity (H3-trimethyl-K4 specific)
GO:0034648 IDA histone demethylase activity (H3-dimethyl-K4 specific)
GO:0034720 IDA histone H3-K4 demethylation
GO:0034721 IDA histone H3-K4 demethylation, trimethyl-H3-K4-specific
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000047714 Kdm5b-001 protein_coding Mus_musculus 0 6488
ENSMUST00000112198 Kdm5b-003 protein_coding Mus_musculus 0 5616
ENSMUST00000112197 Kdm5b-002 retained_intron Mus_musculus 0 2207
ENSMUST00000133725 Kdm5b-004 retained_intron Mus_musculus 0 612
ENSMUST00000082177 Kdm5c-004 protein_coding Mus_musculus 0 420
ENSMUST00000112588 Kdm5c-001 protein_coding Mus_musculus 0 420
ENSMUST00000112584 Kdm5c-002 protein_coding Mus_musculus 0 420
ENSMUST00000186128 Kdm5b-005 retained_intron Mus_musculus 0 226

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