C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: clathrin, light chain A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000122705 CLTA 9606 + 9:36190856-36304781 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000242285 CLTA-001 36190937-36212059 protein_coding
  ENST00000345519 CLTA-002 36190923-36212056 protein_coding
  ENST00000396603 CLTA-004 36190963-36212059 protein_coding
  ENST00000433436 CLTA-201 36190856-36212061 protein_coding
  ENST00000464497 CLTA-008 36190931-36304781 nonsense_mediated_decay
  ENST00000466396 CLTA-005 36190963-36211784 protein_coding
  ENST00000470744 CLTA-003 36190932-36212058 protein_coding
  ENST00000493185 CLTA-007 36191165-36212057 nonsense_mediated_decay
  ENST00000538225 CLTA-202 36190856-36212061 protein_coding
  ENST00000540080 CLTA-203 36190856-36212061 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000242285ENST00000345519ENST00000396603ENST00000466396ENST00000470744ENST00000493185ENST00000538225ENST00000540080
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000242285 N/A N/A N/A 7.063±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000345519 82.256±0.00 90.324±0.00 7.000±0.00 27.007±17.00 53.721±32.62 58.590±43.02 13.241±9.65 64.618±47.19 26.702±16.35 45.082±34.69 9.142±6.38 144.392±80.09 271.296±71.58 107.765±11.66
ENST00000396603 N/A N/A N/A 22.296±11.57 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000466396 N/A N/A N/A 83.150±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000470744 N/A N/A N/A 4.904±0.00 N/A N/A N/A N/A N/A N/A 9.085±0.00 N/A N/A N/A
ENST00000493185 N/A 17.111±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 20.473±0.00
ENST00000538225 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.590±0.00 N/A N/A N/A
ENST00000540080 N/A N/A N/A N/A N/A N/A N/A N/A 11.363±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006K2 CIL_0006K2_0001 CGP 9:36169394-36304781
CIL_0006K3 CIL_0006K3_0001 CGP 9:36190856-36304781

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006886 IEA intracellular protein transport
GO:0006892 TAS post-Golgi vesicle-mediated transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0016020 IDA membrane
GO:0016023 ISS cytoplasmic membrane-bounded vesicle
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0030118 NAS clathrin coat
GO:0030130 IEA clathrin coat of trans-Golgi network vesicle
GO:0030132 IEA clathrin coat of coated pit
GO:0030136 IEA clathrin-coated vesicle
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0032050 IPI clathrin heavy chain binding
GO:0032588 TAS trans-Golgi network membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0042277 IEA peptide binding
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0061024 TAS membrane organization
GO:0071439 IDA clathrin complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045618 clta clathrin, light chain (Lca) protein_coding Danio_rerio
ENSMUSG00000028478 Clta clathrin, light polypeptide (Lca) protein_coding Mus_musculus

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