C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acyl-CoA synthetase long-chain family member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000123983 ACSL3 9606 + 2:222860934-222944639 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000357430 ACSL3-001 222860934-222944639 protein_coding
  ENST00000392066 ACSL3-002 222860942-222942222 protein_coding
  ENST00000407441 ACSL3-007 222924554-222941527 protein_coding
  ENST00000413316 ACSL3-003 222861563-222909036 protein_coding
  ENST00000421680 ACSL3-005 222920954-222927053 protein_coding
  ENST00000463813 ACSL3-004 222917688-222919104 retained_intron
  ENST00000474422 ACSL3-008 222930611-222933723 retained_intron
  ENST00000495541 ACSL3-009 222933018-222941824 retained_intron
  ENST00000535678 ACSL3-010 222861026-222909059 protein_coding
  ENST00000540115 ACSL3-012 222909616-222921353 protein_coding
  ENST00000542810 ACSL3-011 222909085-222916680 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000357430ENST00000392066ENST00000407441ENST00000495541
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000357430 2.111±0.00 N/A N/A 12.455±4.28 1.173±0.21 2.377±0.00 3.359±0.35 2.287±0.00 3.272±1.21 3.566±1.78 N/A 5.746±0.90 3.301±0.77 2.525±0.00
ENST00000392066 6.131±0.00 3.977±0.00 4.708±0.00 9.354±0.09 6.659±1.68 3.713±0.00 5.100±0.00 9.196±0.24 5.697±4.09 9.233±0.54 2.775±0.22 8.825±4.42 12.325±1.91 9.698±1.79
ENST00000407441 N/A N/A N/A N/A 16.015±0.00 N/A N/A N/A N/A N/A N/A 23.047±0.00 15.083±0.00 18.004±0.00
ENST00000495541 N/A 5.709±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006XK CIL_0006XK_0001 CGP 2:222671738-222944639
CIL_00041H CIL_00041H_0002 CGP 2:222860934-223198399

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004467 IMP long-chain fatty acid-CoA ligase activity
GO:0005524 IEA ATP binding
GO:0005741 IEA mitochondrial outer membrane
GO:0005777 IEA peroxisome
GO:0005783 IDA endoplasmic reticulum
GO:0005794 IDA Golgi apparatus
GO:0005811 IDA lipid particle
GO:0006633 IEA fatty acid biosynthetic process
GO:0007420 IEA brain development
GO:0007584 IEA response to nutrient
GO:0008152 IEA metabolic process
GO:0014070 IEA response to organic cyclic compound
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0034379 IMP very-low-density lipoprotein particle assembly
GO:0042998 IMP positive regulation of Golgi to plasma membrane protein transport
GO:0044539 IDA long-chain fatty acid import
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051047 IMP positive regulation of secretion
GO:2001247 IMP positive regulation of phosphatidylcholine biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014674 acsl3b acyl-CoA synthetase long-chain family member 3b protein_coding Danio_rerio
ENSDARG00000032079 acsl3a acyl-CoA synthetase long-chain family member 3a protein_coding Danio_rerio
ENSMUSG00000032883 Acsl3 acyl-CoA synthetase long-chain family member 3 protein_coding Mus_musculus

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