C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor coactivator 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124151 NCOA3 9606 + 20:47501902-47656877 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000371997 NCOA3-002 47501941-47655742 protein_coding
  ENST00000371998 NCOA3-003 47501927-47653619 protein_coding
  ENST00000372004 NCOA3-001 47501902-47656877 protein_coding
  ENST00000490248 NCOA3-004 47622958-47624073 processed_transcript
  ENST00000497292 NCOA3-005 47627002-47628790 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000371997ENST00000371998ENST00000372004
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000371997 N/A 2.056±0.00 0.896±0.00 N/A N/A N/A N/A 1.822±0.00 N/A N/A 3.563±0.00 N/A N/A
ENST00000371998 N/A N/A N/A 3.599±0.00 3.736±0.00 1.974±0.00 1.818±0.00 4.412±0.00 7.559±0.00 2.324±1.61 5.364±0.00 N/A N/A
ENST00000372004 10.023±0.00 N/A 3.215±0.00 4.861±0.00 4.829±1.84 3.397±2.03 2.454±0.00 3.205±1.21 5.260±1.18 6.149±0.00 5.252±0.90 7.021±3.65 4.989±1.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NW CIL_0008NW_0001 VISTA 20:47083832-47684912
CIL_0006IW CIL_0006IW_0002 CGP 20:47209214-47656877
CIL_0001Y0 CIL_0001Y0_0001 CGP 20:47501902-47786616

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IEA chromatin binding
GO:0003713 NAS:IEA transcription coactivator activity
GO:0004402 IDA histone acetyltransferase activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0010628 IMP positive regulation of gene expression
GO:0016573 IEA histone acetylation
GO:0016922 IPI ligand-dependent nuclear receptor binding
GO:0030374 IEA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030521 NAS androgen receptor signaling pathway
GO:0035257 IDA:IEA nuclear hormone receptor binding
GO:0035264 IEA multicellular organism growth
GO:0035624 TAS receptor transactivation
GO:0045618 IMP positive regulation of keratinocyte differentiation
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046966 NAS thyroid hormone receptor binding
GO:0046983 IEA protein dimerization activity
GO:0047485 IPI protein N-terminus binding
GO:0048589 IEA developmental growth
GO:0050681 NAS androgen receptor binding
GO:0060068 IEA vagina development
GO:0060713 IEA labyrinthine layer morphogenesis
GO:0060744 IEA mammary gland branching involved in thelarche
GO:2001141 IMP regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077404 ncoa3 nuclear receptor coactivator 3 protein_coding Danio_rerio
ENSMUSG00000027678 Ncoa3 nuclear receptor coactivator 3 protein_coding Mus_musculus

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