C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: general transcription factor IIF, polypeptide 1, 74kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125651 GTF2F1 9606 - 19:6379569-6393981 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000394456 GTF2F1-001 6379569-6393460 protein_coding
  ENST00000593678 GTF2F1-006 6379878-6391952 protein_coding
  ENST00000594213 GTF2F1-008 6380190-6381820 retained_intron
  ENST00000594965 GTF2F1-007 6380391-6381775 retained_intron
  ENST00000595047 GTF2F1-005 6381413-6393205 protein_coding
  ENST00000598607 GTF2F1-003 6387505-6393981 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000394456ENST00000593678ENST00000594965ENST00000595047ENST00000598607
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000394456 6.674±0.00 9.912±0.00 0.314±0.00 6.804±4.98 2.965±2.32 15.088±0.00 2.354±1.63 15.828±0.00 7.614±0.00 8.050±0.00 8.124±0.00 21.055±20.56 19.682±7.06 21.584±4.84
ENST00000593678 6.067±0.00 15.802±0.00 N/A 12.051±9.90 10.504±0.00 14.488±13.97 4.242±0.00 10.270±0.00 6.731±0.00 2.441±2.17 4.611±3.73 29.929±8.02 9.205±3.19 22.429±0.00
ENST00000594965 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 12.396±0.00 8.923±0.00 27.253±0.17
ENST00000595047 N/A N/A 1.407±0.00 7.031±5.18 0.957±0.00 0.761±0.00 N/A N/A N/A 1.754±0.00 2.984±0.00 N/A N/A 11.837±0.00
ENST00000598607 N/A N/A 1.461±0.00 N/A N/A N/A N/A 0.645±0.00 4.171±0.00 1.391±0.00 N/A 2.161±0.00 17.466±0.00 54.719±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003WG CIL_0003WG_0001 CGP 19:6375148-6393981
CIL_0003WB CIL_0003WB_0001 CGP 19:6379569-6424794

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003677 IEA DNA binding
GO:0003713 TAS transcription coactivator activity
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005634 IEA:IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005674 TAS transcription factor TFIIF complex
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006367 IEA:TAS transcription initiation from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006370 TAS 7-methylguanosine mRNA capping
GO:0008134 IPI transcription factor binding
GO:0008380 TAS RNA splicing
GO:0009615 IEP response to virus
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0019211 IDA phosphatase activator activity
GO:0030054 IDA cell junction
GO:0032968 IEA positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043085 IDA positive regulation of catalytic activity
GO:0044822 IDA poly(A) RNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032129 gtf2f1 general transcription factor IIF, polypeptide 1 protein_coding Danio_rerio
ENSMUSG00000002658 Gtf2f1 general transcription factor IIF, polypeptide 1 protein_coding Mus_musculus

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