C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: minichromosome maintenance complex component 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000125885 MCM8 9606 + 20:5950652-5995894 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265187 MCM8-002 5950931-5995206 protein_coding
  ENST00000378883 MCM8-201 5950652-5995206 protein_coding
  ENST00000378886 MCM8-202 5950652-5995206 protein_coding
  ENST00000378896 MCM8-203 5950652-5995206 protein_coding
  ENST00000610722 MCM8-001 5950652-5995894 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000265187ENST00000378883ENST00000378886ENST00000378896ENST00000610722
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000265187 0.383±0.00 N/A N/A 0.330±0.00 0.405±0.00 0.471±0.00 0.518±0.06 0.271±0.00 0.415±0.00 2.711±3.04 N/A 4.481±2.90
ENST00000378883 N/A N/A 0.088±0.00 N/A N/A N/A N/A 0.131±0.00 N/A N/A N/A N/A
ENST00000378886 N/A N/A 0.111±0.00 0.812±0.00 0.178±0.00 N/A 0.170±0.00 0.069±0.00 N/A N/A 0.153±0.00 0.897±0.00
ENST00000378896 N/A N/A 0.222±0.16 N/A 1.031±0.00 0.304±0.10 N/A N/A 0.215±0.00 1.055±0.00 0.530±0.05 N/A
ENST00000610722 N/A 0.508±0.00 0.081±0.00 N/A N/A N/A N/A N/A 0.288±0.02 2.117±1.57 0.982±0.00 2.905±1.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002W4 CIL_0002W4_0001 CGP 20:5937235-5995894
CIL_0007A0 CIL_0007A0_0002 CGP 20:5950652-6040053

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000278 TAS mitotic cell cycle
GO:0000724 IEA double-strand break repair via homologous recombination
GO:0003677 IEA DNA binding
GO:0004386 IEA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006260 TAS:IEA DNA replication
GO:0006271 TAS DNA strand elongation involved in DNA replication
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007292 ISS female gamete generation
GO:0015979 IEA photosynthesis
GO:0015995 IEA chlorophyll biosynthetic process
GO:0016851 IEA magnesium chelatase activity
GO:0016887 IEA ATPase activity
GO:0048232 ISS male gamete generation
GO:0097362 IDA MCM8-MCM9 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074326 mcm8 minichromosome maintenance complex component 8 protein_coding Danio_rerio
ENSMUSG00000027353 Mcm8 minichromosome maintenance deficient 8 (S. cerevisiae) protein_coding Mus_musculus

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