C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: minichromosome maintenance deficient 8 (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027353 Mcm8 10090 + 2:132816141-132844197 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028831 Mcm8-001 132816141-132843895 protein_coding
  ENSMUST00000066559 Mcm8-002 132816141-132844197 protein_coding
  ENSMUST00000135685 Mcm8-003 132816224-132818025 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028831ENSMUST00000066559
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028831 1.076±0.22 N/A 0.927±0.05 1.631±0.23 0.640±0.08 0.454±0.04 0.550±0.08 0.410±0.25 2.040±1.78 0.166±0.00 0.527±0.11 2.172±1.06 3.355±2.22 0.711±0.41
ENSMUST00000066559 1.146±0.07 1.938±0.43 0.185±0.00 0.365±0.00 0.600±0.20 0.669±0.32 N/A 0.498±0.11 0.487±0.27 0.356±0.11 0.149±0.08 2.085±0.91 N/A 1.349±0.64

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002W4 CIL_0002W4_0002 CGP 2:132804207-132844197
CIL_0007A0 CIL_0007A0_0003 CGP 2:132816141-132866785

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0003674 ND molecular_function
GO:0003677 IEA DNA binding
GO:0004386 IEA helicase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0006260 IEA DNA replication
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007049 IEA cell cycle
GO:0007292 IMP female gamete generation
GO:0048232 IMP male gamete generation
GO:0097362 IDA MCM8-MCM9 complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074326 mcm8 minichromosome maintenance complex component 8 protein_coding Danio_rerio
ENSG00000125885 MCM8 minichromosome maintenance complex component 8 protein_coding Homo_sapiens

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