C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: centrosomal protein 250kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000126001 CEP250 9606 + 20:35455164-35519280 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000397524 CEP250-006 35455724-35470132 protein_coding
  ENST00000397527 CEP250-001 35455329-35519280 protein_coding
  ENST00000420564 CEP250-003 35455175-35466054 protein_coding
  ENST00000422671 CEP250-011 35502906-35511640 protein_coding
  ENST00000425096 CEP250-010 35474001-35478096 protein_coding
  ENST00000425525 CEP250-004 35497809-35502804 nonsense_mediated_decay
  ENST00000425934 CEP250-012 35462265-35478063 protein_coding
  ENST00000446710 CEP250-002 35455164-35466204 protein_coding
  ENST00000461386 CEP250-013 35455597-35478066 nonsense_mediated_decay
  ENST00000465987 CEP250-008 35465764-35467316 processed_transcript
  ENST00000474829 CEP250-009 35469846-35472785 retained_intron
  ENST00000476146 CEP250-007 35455201-35462304 processed_transcript
  ENST00000487467 CEP250-005 35494378-35496637 retained_intron
  ENST00000621352 CEP250-014 35509998-35517531 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000397527ENST00000422671ENST00000425525ENST00000425934ENST00000461386ENST00000465987
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000397527 N/A N/A 0.457±0.00 N/A 0.317±0.14 0.120±0.00 N/A 0.209±0.00 0.569±0.00 0.397±0.15 N/A 1.488±0.78 0.157±0.00 3.243±0.00
ENST00000422671 2.421±0.00 7.347±0.00 N/A 3.095±0.00 3.123±0.00 2.586±1.83 0.920±0.72 2.126±1.72 0.726±0.00 2.580±2.05 0.909±0.31 6.093±2.03 2.095±0.54 12.530±3.07
ENST00000425525 N/A N/A N/A N/A N/A N/A N/A 1.696±0.00 N/A N/A N/A N/A N/A N/A
ENST00000425934 N/A N/A 1.317±0.00 0.842±0.00 N/A N/A 0.594±0.30 N/A N/A N/A N/A 1.635±0.00 N/A N/A
ENST00000461386 N/A N/A N/A 1.311±0.68 2.850±0.00 N/A N/A N/A 1.931±0.00 N/A N/A N/A N/A N/A
ENST00000465987 N/A N/A 10.269±0.00 N/A N/A N/A N/A 4.663±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EI CIL_0008EI_0001 VISTA 20:35018152-35620688
CIL_0002I5 CIL_0002I5_0001 CGP 20:35433347-35519280
CIL_0005FS CIL_0005FS_0001 CGP 20:35455164-35529652

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000278 IDA mitotic cell cycle
GO:0005515 IPI protein binding
GO:0005813 IDA centrosome
GO:0005814 IEA centriole
GO:0005815 NAS microtubule organizing center
GO:0005829 TAS cytosol
GO:0005929 IEA cilium
GO:0008022 IPI protein C-terminus binding
GO:0008104 IMP protein localization
GO:0010457 IMP centriole-centriole cohesion
GO:0019901 IPI protein kinase binding
GO:0019904 IPI protein domain specific binding
GO:0030997 IDA regulation of centriole-centriole cohesion
GO:0031616 IEA spindle pole centrosome
GO:0033365 IMP protein localization to organelle
GO:0043234 IMP protein complex
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020834 CEP250 centrosomal protein 250kDa protein_coding Danio_rerio
ENSMUSG00000038241 Cep250 centrosomal protein 250 protein_coding Mus_musculus

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