C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: INO80 complex subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000128908 INO80 9606 - 15:40978880-41116354 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361937 INO80-001 40978880-41116354 protein_coding
  ENST00000401393 INO80-201 40978893-41116153 protein_coding
  ENST00000557849 INO80-006 40997577-41027599 nonsense_mediated_decay
  ENST00000558270 INO80-010 40979911-40983219 retained_intron
  ENST00000558357 INO80-002 40979466-41116132 nonsense_mediated_decay
  ENST00000559995 INO80-005 41049939-41069622 nonsense_mediated_decay
  ENST00000560689 INO80-009 40980302-40983986 retained_intron
  ENST00000560799 INO80-008 40984344-40997710 retained_intron
  ENST00000561172 INO80-004 41069512-41072015 retained_intron
  ENST00000561244 INO80-007 40985349-41005357 processed_transcript
  ENST00000616814 INO80-202 40980223-41116132 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361937ENST00000401393ENST00000558357ENST00000560799ENST00000616814
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361937 2.380±0.00 0.998±0.00 N/A 1.108±0.37 2.162±0.99 1.730±0.31 1.737±1.16 N/A N/A 1.292±0.00 4.695±0.00 2.321±1.26 1.472±0.26 2.291±0.13
ENST00000401393 N/A N/A N/A 0.735±0.02 N/A N/A N/A 0.863±0.00 1.079±0.00 0.887±0.27 N/A 0.969±0.00 0.692±0.00 N/A
ENST00000558357 0.912±0.00 1.629±0.00 N/A 0.636±0.00 1.009±0.00 N/A N/A 0.961±0.00 N/A N/A 0.356±0.00 0.669±0.00 N/A N/A
ENST00000560799 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.577±0.00 6.152±0.00 15.437±0.00
ENST00000616814 N/A N/A 0.574±0.00 N/A N/A N/A N/A 1.719±0.00 N/A 3.004±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005IM CIL_0005IM_0002 CGP 15:40952962-41116354
CIL_000798 CIL_000798_0001 CGP 15:40978880-41230743

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000070 IMP mitotic sister chromatid segregation
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0003677 IDA:IEA DNA binding
GO:0003678 IDA DNA helicase activity
GO:0003779 IEA actin binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005874 IEA microtubule
GO:0006200 IDA ATP catabolic process
GO:0006302 IMP double-strand break repair
GO:0006338 IDA chromatin remodeling
GO:0008152 IEA metabolic process
GO:0010571 IMP positive regulation of nuclear cell cycle DNA replication
GO:0016817 IEA hydrolase activity, acting on acid anhydrides
GO:0016887 IDA ATPase activity
GO:0030307 IMP positive regulation of cell growth
GO:0031011 IDA Ino80 complex
GO:0032508 IDA DNA duplex unwinding
GO:0034644 IMP cellular response to UV
GO:0043014 IMP alpha-tubulin binding
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0051225 IMP spindle assembly
GO:0070914 IMP UV-damage excision repair
GO:0071479 IMP cellular response to ionizing radiation
GO:2000045 IMP regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070432 ino80 INO80 homolog (S. cerevisiae) protein_coding Danio_rerio
ENSMUSG00000034154 Ino80 INO80 homolog (S. cerevisiae) protein_coding Mus_musculus

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