C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: forkhead box A1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000250448 FOXA1-001 ENSG00000129514 9606 - 14:37589984-37595034 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonKidneyLiverLungOvaryENST00000250448
Transcript ID Adipose Bladder Brain Breast Colon Kidney Liver Lung Ovary
ENST00000250448 0.046±0.00 0.022±0.00 0.043±0.00 1.527±0.00 1.748±0.00 0.897±0.66 7.158±5.63 3.086±2.42 1.636±1.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005R8 CIL_0005R8_0002 CGP 14:37197913-37596059
CIL_0005R7 CIL_0005R7_0002 CGP 14:37589984-38041442

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005902 IEA microvillus
GO:0006338 ISS chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0010468 IEA regulation of gene expression
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0019904 IEA protein domain specific binding
GO:0021904 IEA dorsal/ventral neural tube patterning
GO:0030324 IEA lung development
GO:0032355 IDA response to estradiol
GO:0033148 IMP positive regulation of intracellular estrogen receptor signaling pathway
GO:0035239 IEA tube morphogenesis
GO:0042445 IEA hormone metabolic process
GO:0042593 IEA glucose homeostasis
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0048665 IEA neuron fate specification
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051726 IEA regulation of cell cycle
GO:0060441 IEA epithelial tube branching involved in lung morphogenesis
GO:0060487 IEA lung epithelial cell differentiation
GO:0060528 IEA secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060738 IEA epithelial-mesenchymal signaling involved in prostate gland development
GO:0060740 IEA prostate gland epithelium morphogenesis
GO:0060741 IEA prostate gland stromal morphogenesis
GO:0060743 IEA epithelial cell maturation involved in prostate gland development
GO:0061448 IEA connective tissue development
GO:2000049 IC positive regulation of cell-cell adhesion mediated by cadherin

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000044380 Foxa1-201 protein_coding Mus_musculus 0 2662
ENSMUST00000047315 Foxa2-001 protein_coding Mus_musculus 0 442
ENSMUST00000109964 Foxa2-002 protein_coding Mus_musculus 0 442
ENSMUST00000036018 Foxa3-001 protein_coding Mus_musculus 0 333
ENSDART00000010813 foxa3-001 protein_coding Danio_rerio 0 326
ENSMUST00000153321 Foxa3-002 processed_transcript Mus_musculus 0 287
ENSMUST00000146242 Foxa2-003 processed_transcript Mus_musculus 0 276
ENSMUST00000172928 Foxa2-004 protein_coding Mus_musculus 0 257

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