C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin-conjugating enzyme E2D 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131508 UBE2D2 9606 + 5:139526431-139628433 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000253815 UBE2D2-201 139599562-139626801 protein_coding
  ENST00000398733 UBE2D2-001 139561166-139628433 protein_coding
  ENST00000398734 UBE2D2-004 139561726-139627686 nonsense_mediated_decay
  ENST00000505007 UBE2D2-003 139561167-139623444 protein_coding
  ENST00000505548 UBE2D2-002 139562029-139627115 protein_coding
  ENST00000510470 UBE2D2-007 139561724-139614685 retained_intron
  ENST00000511691 UBE2D2-008 139600404-139623662 retained_intron
  ENST00000511725 UBE2D2-006 139526431-139626855 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000253815ENST00000398733ENST00000398734ENST00000505007ENST00000505548ENST00000511691ENST00000511725
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000253815 N/A N/A 10.255±0.00 20.384±0.00 9.036±0.00 16.009±0.00 14.326±5.27 13.000±0.00 18.132±6.02 17.357±2.19 26.437±4.03 42.326±37.93 29.111±0.08 N/A
ENST00000398733 18.497±0.00 23.804±0.00 1.254±0.00 15.449±10.90 9.305±8.44 4.891±0.41 6.627±5.76 8.683±6.41 4.852±2.05 13.385±0.00 9.010±7.88 13.043±9.90 12.588±4.74 22.729±5.75
ENST00000398734 17.986±0.00 26.010±0.00 N/A 22.140±0.00 16.452±0.00 9.221±0.00 4.104±2.81 16.429±0.00 4.347±0.00 7.282±4.69 9.736±0.00 10.701±9.18 16.246±8.84 42.067±2.90
ENST00000505007 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.123±0.00 N/A N/A N/A
ENST00000505548 N/A N/A 1.241±0.00 N/A N/A N/A 0.907±0.00 N/A N/A N/A N/A N/A N/A 17.551±0.00
ENST00000511691 N/A N/A N/A N/A 3.960±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000511725 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 26.387±0.00 32.986±0.00 68.258±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000548 CIL_000548_0001 CGP 5:139475534-139628433
CIL_000549 CIL_000549_0001 CGP 5:139526431-139683882

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000151 IDA ubiquitin ligase complex
GO:0000209 IDA protein polyubiquitination
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006464 TAS cellular protein modification process
GO:0006511 TAS ubiquitin-dependent protein catabolic process
GO:0008152 IEA metabolic process
GO:0016567 IDA protein ubiquitination
GO:0016881 IEA acid-amino acid ligase activity
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0043234 IDA protein complex
GO:0045087 TAS innate immune response
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070062 IDA extracellular vesicular exosome
GO:0070936 IDA protein K48-linked ubiquitination
GO:0071456 TAS cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000028252 ube2d2l ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast), like protein_coding Danio_rerio
ENSMUSG00000063447 Ube2d2b ubiquitin-conjugating enzyme E2D 2B protein_coding Mus_musculus
ENSMUSG00000091896 Ube2d2a ubiquitin-conjugating enzyme E2D 2A protein_coding Mus_musculus

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