C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase 1, regulatory (inhibitor) subunit 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000131771 PPP1R1B 9606 + 17:39626740-39636626 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254079 PPP1R1B-001 39626924-39636626 protein_coding
  ENST00000394265 PPP1R1B-005 39628498-39636625 protein_coding
  ENST00000394267 PPP1R1B-002 39628498-39636626 protein_coding
  ENST00000492037 PPP1R1B-006 39629405-39636624 retained_intron
  ENST00000579000 PPP1R1B-008 39627200-39636622 protein_coding
  ENST00000580029 PPP1R1B-007 39632138-39636625 retained_intron
  ENST00000580772 PPP1R1B-011 39628526-39630452 retained_intron
  ENST00000580825 PPP1R1B-013 39626740-39636000 protein_coding
  ENST00000582680 PPP1R1B-014 39626952-39634084 protein_coding
  ENST00000583446 PPP1R1B-012 39629374-39635721 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254079ENST00000394265ENST00000394267ENST00000492037ENST00000579000ENST00000580029ENST00000580772ENST00000580825ENST00000582680ENST00000583446
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254079 11.305±0.00 N/A N/A 85.769±68.40 28.022±26.93 15.393±9.19 0.529±0.00 2.526±0.00 N/A 16.267±0.00 N/A 14.869±0.00 N/A 5.621±0.00
ENST00000394265 N/A N/A N/A N/A N/A N/A N/A 1.483±0.00 N/A N/A 0.303±0.00 1.417±0.55 0.150±0.00 3.868±0.00
ENST00000394267 N/A N/A N/A N/A N/A 6.043±0.00 N/A N/A N/A N/A N/A 0.688±0.26 N/A 0.957±0.00
ENST00000492037 N/A N/A N/A N/A N/A N/A 0.043±0.00 N/A N/A N/A N/A 0.614±0.00 N/A N/A
ENST00000579000 7.437±0.00 0.370±0.00 N/A N/A 0.998±0.00 18.855±0.00 0.108±0.00 2.975±0.00 0.311±0.00 2.853±2.09 N/A 2.701±0.00 N/A 5.180±4.10
ENST00000580029 N/A N/A N/A N/A 0.250±0.00 N/A 0.025±0.00 N/A 0.238±0.00 N/A N/A 0.303±0.00 N/A N/A
ENST00000580772 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.381±0.00 N/A N/A N/A N/A
ENST00000580825 N/A N/A 0.245±0.00 N/A N/A N/A N/A N/A 0.051±0.00 N/A 0.126±0.00 5.931±0.00 0.201±0.00 N/A
ENST00000582680 N/A N/A N/A N/A N/A N/A N/A N/A 2.976±0.00 N/A 0.438±0.00 N/A N/A 1.528±0.00
ENST00000583446 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.507±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008SN CIL_0008SN_0001 VISTA 17:39110111-39710718
CIL_00080Z CIL_00080Z_0001 VISTA 17:39318232-39918735
CIL_00098W CIL_00098W_0001 VISTA 17:39359510-39962707
CIL_0007WH CIL_0007WH_0001 VISTA 17:39374871-39978277
CIL_00061T CIL_00061T_0001 CGP 17:39603536-39636626
CIL_0000TI CIL_0000TI_0002 CGP 17:39626740-39663484

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001975 IEA response to amphetamine
GO:0004860 TAS protein kinase inhibitor activity
GO:0004864 TAS:IEA protein phosphatase inhibitor activity
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006469 TAS negative regulation of protein kinase activity
GO:0007165 TAS:IEA signal transduction
GO:0007621 IEA negative regulation of female receptivity
GO:0008542 IEA visual learning
GO:0008599 TAS protein phosphatase type 1 regulator activity
GO:0031748 IEA D1 dopamine receptor binding
GO:0031749 IEA D2 dopamine receptor binding
GO:0031750 IEA D3 dopamine receptor binding
GO:0031751 IEA D4 dopamine receptor binding
GO:0031752 IEA D5 dopamine receptor binding
GO:0035556 IEA intracellular signal transduction
GO:0043025 IEA neuronal cell body
GO:0043086 TAS negative regulation of catalytic activity
GO:0050790 TAS regulation of catalytic activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076280 ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B protein_coding Danio_rerio
ENSMUSG00000061718 Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B protein_coding Mus_musculus

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