C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: regulatory factor X, 1 (influences HLA class II expression)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132005 HGNC:9982 9606 - 19:13961538-14007039 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254325 HGNC:9982-001 13961538-14006285 protein_coding
  ENST00000586913 HGNC:9982-006 13998168-14007039 processed_transcript
  ENST00000588520 HGNC:9982-007 13963704-13964055 retained_intron
  ENST00000588885 HGNC:9982-005 13983313-14006262 protein_coding
  ENST00000589239 HGNC:9982-002 13969640-14006322 retained_intron
  ENST00000589760 HGNC:9982-004 13983069-14006267 retained_intron
  ENST00000589937 HGNC:9982-003 13983028-14006289 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254325ENST00000589239ENST00000589760
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254325 3.692±0.00 3.212±0.00 0.416±0.00 1.384±0.00 2.474±2.22 0.560±0.13 1.312±1.05 0.688±0.32 1.421±0.00 0.071±0.00 3.010±0.00 2.394±2.06 6.005±0.50 7.012±3.72
ENST00000589239 N/A N/A N/A N/A N/A N/A N/A N/A 0.064±0.00 N/A N/A N/A N/A N/A
ENST00000589760 N/A N/A 0.739±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016Z CIL_00016Z_0002 CGP 19:13952492-14007039
CIL_00058X CIL_00058X_0002 CGP 19:13961538-14031042

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 IEA DNA binding
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006955 TAS immune response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005883 rfx1a regulatory factor X, 1a (influences HLA class II expression) protein_coding Danio_rerio
ENSDARG00000075904 rfx1b regulatory factor X, 1b (influences HLA class II expression) protein_coding Danio_rerio
ENSMUSG00000031706 Rfx1 regulatory factor X, 1 (influences HLA class II expression) protein_coding Mus_musculus

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