C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein tyrosine phosphatase, receptor type, E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132334 PTPRE 9606 + 10:127907061-128085855 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254667 PTPRE-003 127907061-128085855 protein_coding
  ENST00000306042 PTPRE-004 128047570-128085855 protein_coding
  ENST00000442830 PTPRE-007 127907152-128049666 protein_coding
  ENST00000455661 PTPRE-006 127998126-128056163 protein_coding
  ENST00000463727 PTPRE-001 128068382-128072682 retained_intron
  ENST00000467366 PTPRE-010 128047406-128056171 protein_coding
  ENST00000471218 PTPRE-008 127987344-128056170 protein_coding
  ENST00000479896 PTPRE-005 128047631-128085855 nonsense_mediated_decay
  ENST00000487428 PTPRE-002 128047619-128049635 retained_intron
  ENST00000492479 PTPRE-011 128062919-128070841 retained_intron
  ENST00000495530 PTPRE-009 128047629-128070375 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254667ENST00000306042ENST00000479896
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254667 1.988±0.00 4.053±0.00 N/A 3.984±0.12 0.902±0.00 0.756±0.06 1.806±1.28 0.838±0.00 0.182±0.00 1.936±0.95 N/A 1.539±1.21 0.584±0.00 0.756±0.00
ENST00000306042 N/A 1.670±0.00 1.166±0.00 N/A 0.711±0.05 1.362±1.10 0.844±0.13 0.798±0.13 1.086±0.78 5.538±0.00 0.112±0.00 1.535±0.76 1.610±0.27 0.627±0.09
ENST00000479896 1.321±0.00 1.208±0.00 N/A 1.263±0.00 0.551±0.00 N/A N/A N/A N/A 1.809±0.00 N/A 0.396±0.16 N/A 0.185±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00083E CIL_00083E_0001 VISTA 10:127865799-128466830
CIL_0001LJ CIL_0001LJ_0001 CGP 10:127877841-128085855
CIL_00028S CIL_00028S_0001 CGP 10:127907061-128126385

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004725 IEA protein tyrosine phosphatase activity
GO:0005001 TAS transmembrane receptor protein tyrosine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006470 TAS:IEA protein dephosphorylation
GO:0007185 IEA transmembrane receptor protein tyrosine phosphatase signaling pathway
GO:0016021 IEA integral component of membrane
GO:0016311 IEA dephosphorylation
GO:0016791 IEA phosphatase activity
GO:0033003 IEA regulation of mast cell activation
GO:0035335 IEA peptidyl-tyrosine dephosphorylation
GO:0042803 IEA protein homodimerization activity
GO:0046627 ISS negative regulation of insulin receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015891 ptprea protein tyrosine phosphatase, receptor type, E, a protein_coding Danio_rerio
ENSDARG00000021151 ptpreb protein tyrosine phosphatase, receptor type, E, b protein_coding Danio_rerio
ENSMUSG00000041836 Ptpre protein tyrosine phosphatase, receptor type, E protein_coding Mus_musculus

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