C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: synaptosomal-associated protein, 25kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132639 SNAP25 9606 + 20:10218830-10307418 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000254976 SNAP25-003 10218830-10307418 protein_coding
  ENST00000304886 SNAP25-004 10218833-10307418 protein_coding
  ENST00000430336 SNAP25-002 10219066-10293278 protein_coding
  ENST00000492814 SNAP25-001 10275519-10278069 processed_transcript
  ENST00000495883 SNAP25-005 10296230-10307418 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000254976ENST00000304886ENST00000430336ENST00000492814ENST00000495883
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000254976 N/A 0.142±0.00 N/A 466.339±194.05 0.149±0.00 1.131±0.00 N/A 0.093±0.00 0.297±0.17 0.709±0.00 0.172±0.01 N/A 0.402±0.00 1.415±1.07
ENST00000304886 0.050±0.00 0.106±0.00 0.237±0.00 67.094±0.00 0.331±0.20 1.578±0.95 0.108±0.01 0.497±0.00 N/A 0.505±0.00 N/A 1.365±0.86 0.340±0.21 2.244±1.22
ENST00000430336 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.377±0.00 0.045±0.00 N/A 0.905±0.00
ENST00000492814 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.491±0.00 N/A N/A
ENST00000495883 0.037±0.00 N/A N/A N/A 0.236±0.16 N/A N/A 0.185±0.00 0.204±0.00 0.166±0.00 N/A 0.543±0.33 N/A 0.397±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001ZQ CIL_0001ZQ_0002 CGP 20:9986126-10307418
CIL_00043K CIL_00043K_0001 CGP 20:10218830-10434222

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000149 IEA SNARE binding
GO:0001504 NAS neurotransmitter uptake
GO:0005515 IPI:IEA protein binding
GO:0005737 ISS cytoplasm
GO:0005802 IEA trans-Golgi network
GO:0005886 TAS plasma membrane
GO:0006112 TAS energy reserve metabolic process
GO:0007268 NAS synaptic transmission
GO:0007269 TAS neurotransmitter secretion
GO:0010975 IEA regulation of neuron projection development
GO:0014047 TAS glutamate secretion
GO:0016020 ISS:IEA membrane
GO:0016079 TAS synaptic vesicle exocytosis
GO:0016081 NAS synaptic vesicle docking involved in exocytosis
GO:0016192 IEA vesicle-mediated transport
GO:0030054 IEA cell junction
GO:0030426 ISS growth cone
GO:0031083 IDA BLOC-1 complex
GO:0031201 ISS SNARE complex
GO:0042734 TAS presynaptic membrane
GO:0043005 ISS neuron projection
GO:0044281 TAS small molecule metabolic process
GO:0045202 IEA synapse
GO:0048306 ISS calcium-dependent protein binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050796 TAS regulation of insulin secretion
GO:0060291 IEA long-term synaptic potentiation
GO:0070032 IEA synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex
GO:0070201 IEA regulation of establishment of protein localization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020609 snap25a synaptosome-associated protein 25a protein_coding Danio_rerio
ENSDARG00000058117 snap25b synaptosome-associated protein 25b protein_coding Danio_rerio
ENSMUSG00000027273 Snap25 synaptosomal-associated protein 25 protein_coding Mus_musculus

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