C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132964 CDK8 9606 + 13:26254139-26405238 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000381527 CDK8-001 26254139-26405238 protein_coding
  ENST00000465820 CDK8-005 26385211-26401599 processed_transcript
  ENST00000477277 CDK8-002 26396217-26405178 processed_transcript
  ENST00000477290 CDK8-004 26337567-26400515 processed_transcript
  ENST00000480323 CDK8-003 26400073-26405238 processed_transcript
  ENST00000536792 CDK8-201 26254642-26404081 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381527ENST00000465820ENST00000477277ENST00000480323ENST00000536792
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381527 2.049±0.00 1.534±0.00 N/A 1.678±0.53 2.556±1.25 6.531±4.16 2.456±0.00 1.868±1.58 1.744±0.60 1.748±0.00 1.722±0.00 2.826±0.78 2.135±0.28 6.198±0.00
ENST00000465820 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 17.801±0.00 6.280±0.00 10.547±0.00
ENST00000477277 N/A 0.830±0.00 0.542±0.00 N/A N/A N/A N/A N/A 0.511±0.00 1.225±0.00 N/A 1.393±0.00 0.803±0.23 N/A
ENST00000480323 N/A 0.626±0.00 N/A N/A N/A 0.607±0.00 N/A N/A N/A N/A 0.515±0.00 0.674±0.00 N/A N/A
ENST00000536792 N/A N/A 0.699±0.00 N/A 3.005±0.00 1.248±0.00 1.373±0.00 1.387±0.00 2.496±0.00 2.963±0.00 N/A 5.555±5.21 6.831±0.00 14.237±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004MF CIL_0004MF_0001 CGP 13:26132115-26405238
CIL_0000G3 CIL_0000G3_0002 CGP 13:26254139-26688948

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0008353 IEA RNA polymerase II carboxy-terminal domain kinase activity
GO:0010467 TAS gene expression
GO:0016592 IDA mediator complex
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0045944 TAS positive regulation of transcription from RNA polymerase II promoter
GO:0051726 IEA regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016496 cdk8 cyclin-dependent kinase 8 protein_coding Danio_rerio
ENSMUSG00000029635 Cdk8 cyclin-dependent kinase 8 protein_coding Mus_musculus

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