C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cyclin-dependent kinase 8
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000381527 CDK8-001 ENSG00000132964 9606 + 13:26254139-26405238 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000381527
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000381527 2.049±0.00 1.534±0.00 1.678±0.53 2.556±1.25 6.531±4.16 2.456±0.00 1.868±1.58 1.744±0.60 1.748±0.00 1.722±0.00 2.826±0.78 2.135±0.28 6.198±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004MF CIL_0004MF_0001 CGP 13:26132115-26405238
CIL_0000G3 CIL_0000G3_0002 CGP 13:26254139-26688948

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 TAS:IEA protein kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 TAS transcription, DNA-templated
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0007179 TAS transforming growth factor beta receptor signaling pathway
GO:0007219 TAS Notch signaling pathway
GO:0008353 IEA RNA polymerase II carboxy-terminal domain kinase activity
GO:0010467 TAS gene expression
GO:0016592 IDA mediator complex
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0045944 TAS positive regulation of transcription from RNA polymerase II promoter
GO:0051726 IEA regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000031640 Cdk8-001 protein_coding Mus_musculus 0 3151
ENSMUST00000161181 Cdk8-002 protein_coding Mus_musculus 0 2752
ENSMUST00000162494 Cdk8-003 nonsense_mediated_decay Mus_musculus 0 2289
ENSMUST00000159615 Cdk8-004 retained_intron Mus_musculus 0 1840
ENSMUST00000161652 Cdk8-006 protein_coding Mus_musculus 0 1059
ENSDART00000007066 cdk8-001 protein_coding Danio_rerio 0 1042
ENSMUST00000159467 Cdk8-005 protein_coding Mus_musculus 0 510
ENSMUST00000160924 Cdk8-007 retained_intron Mus_musculus 0 239

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