C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029635 Cdk8 10090 + 5:146231230-146302874 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031640 Cdk8-001 146231288-146302874 protein_coding
  ENSMUST00000159467 Cdk8-005 146231385-146271664 protein_coding
  ENSMUST00000159615 Cdk8-004 146294910-146302819 retained_intron
  ENSMUST00000160924 Cdk8-007 146296365-146299512 retained_intron
  ENSMUST00000161181 Cdk8-002 146231250-146302831 protein_coding
  ENSMUST00000161652 Cdk8-006 146231288-146292744 protein_coding
  ENSMUST00000162494 Cdk8-003 146231230-146302874 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031640ENSMUST00000159467ENSMUST00000159615ENSMUST00000161181ENSMUST00000162494
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031640 1.559±0.00 N/A 10.931±0.00 5.011±1.79 2.568±0.00 N/A 1.457±0.17 N/A 9.065±2.73 N/A 1.413±0.80 4.670±0.45 3.719±0.81 2.115±1.31
ENSMUST00000159467 N/A N/A N/A 31.649±0.00 N/A N/A N/A N/A N/A N/A N/A 71.997±0.00 50.837±16.78 19.586±0.00
ENSMUST00000159615 8.961±5.08 46.831±20.71 12.513±0.00 11.792±3.01 12.094±4.97 19.748±6.80 2.676±0.94 11.514±3.19 12.657±4.40 11.410±4.41 0.744±0.02 17.919±7.73 3.652±0.37 5.340±2.73
ENSMUST00000161181 N/A N/A N/A N/A N/A 9.287±0.17 0.569±0.00 2.980±0.00 4.153±1.32 2.922±0.00 1.562±0.00 9.701±7.95 2.399±0.28 1.291±0.57
ENSMUST00000162494 3.244±1.63 15.319±5.61 5.413±0.00 4.545±2.40 3.944±0.64 16.120±2.53 0.561±0.00 4.156±0.74 5.827±3.02 3.161±0.39 0.881±0.44 11.287±4.32 4.481±1.85 2.107±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004MF CIL_0004MF_0002 CGP 5:146209192-146302874
CIL_0000G3 CIL_0000G3_0003 CGP 5:146231230-146472411

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISO nucleus
GO:0005654 TAS nucleoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0008353 IEA RNA polymerase II carboxy-terminal domain kinase activity
GO:0016592 ISO mediator complex
GO:0051726 IEA regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016496 cdk8 cyclin-dependent kinase 8 protein_coding Danio_rerio
ENSG00000132964 CDK8 cyclin-dependent kinase 8 protein_coding Homo_sapiens

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