C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transient receptor potential cation channel, subfamily C, member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133107 TRPC4 9606 - 13:37636636-37870425 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000338947 TRPC4-201 37636641-37869802 protein_coding
  ENST00000355779 TRPC4-002 37636865-37869802 protein_coding
  ENST00000358477 TRPC4-003 37636865-37869802 protein_coding
  ENST00000379673 TRPC4-004 37636865-37869802 protein_coding
  ENST00000379679 TRPC4-006 37636843-37783333 protein_coding
  ENST00000379705 TRPC4-001 37636636-37870425 protein_coding
  ENST00000426868 TRPC4-202 37636843-37869723 protein_coding
  ENST00000488717 TRPC4-005 37636843-37783333 nonsense_mediated_decay
  ENST00000494529 TRPC4-007 37663428-37674370 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000338947ENST00000355779ENST00000358477ENST00000379673ENST00000379679ENST00000379705ENST00000426868ENST00000488717ENST00000494529
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000338947 N/A N/A N/A 0.746±0.00 0.501±0.00 0.372±0.00 N/A 0.266±0.00 N/A N/A N/A 0.105±0.01 0.299±0.15 N/A
ENST00000355779 N/A N/A N/A N/A N/A N/A 0.083±0.00 N/A 0.268±0.00 N/A N/A 0.099±0.08 N/A N/A
ENST00000358477 N/A N/A N/A 0.194±0.00 N/A N/A N/A N/A 0.317±0.00 0.224±0.00 N/A 0.029±0.00 0.994±0.00 N/A
ENST00000379673 N/A N/A 0.036±0.00 N/A N/A N/A 0.090±0.00 N/A N/A 0.585±0.00 0.028±0.00 N/A N/A N/A
ENST00000379679 0.135±0.00 N/A 0.116±0.00 N/A 0.085±0.00 0.332±0.00 0.156±0.00 N/A 0.013±0.00 N/A N/A N/A 0.245±0.00 0.253±0.00
ENST00000379705 N/A 0.103±0.00 N/A 0.221±0.00 N/A 0.137±0.07 0.031±0.00 N/A N/A 2.002±0.00 N/A 0.500±0.03 0.275±0.16 N/A
ENST00000426868 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.126±0.09 0.250±0.00 N/A
ENST00000488717 N/A N/A N/A 0.387±0.00 N/A 0.104±0.00 N/A 0.191±0.00 N/A N/A N/A N/A 0.280±0.06 0.189±0.01
ENST00000494529 N/A N/A N/A N/A N/A N/A N/A 0.430±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006CR CIL_0006CR_0002 CGP 13:37562583-37870425
CIL_0006CS CIL_0006CS_0002 CGP 13:37636636-38363619

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005262 IEA calcium channel activity
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0005901 IEA caveola
GO:0005911 IDA cell-cell junction
GO:0006811 IEA ion transport
GO:0006816 TAS calcium ion transport
GO:0007411 TAS axon guidance
GO:0008013 IPI beta-catenin binding
GO:0009986 IDA cell surface
GO:0014051 IEA gamma-aminobutyric acid secretion
GO:0015279 IMP store-operated calcium channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0030863 IDA cortical cytoskeleton
GO:0034220 TAS ion transmembrane transport
GO:0034704 IDA calcium channel complex
GO:0043234 IEA protein complex
GO:0045121 IEA membrane raft
GO:0045296 IPI cadherin binding
GO:0048709 IEA oligodendrocyte differentiation
GO:0055085 TAS:IEA transmembrane transport
GO:0070509 IDA calcium ion import
GO:0070588 TAS calcium ion transmembrane transport
GO:0070679 IEA inositol 1,4,5 trisphosphate binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062183 trpc4b transient receptor potential cation channel, subfamily C, member 4b protein_coding Danio_rerio
ENSDARG00000070507 TRPC4 (2 of 2) transient receptor potential cation channel, subfamily C, member 4 protein_coding Danio_rerio
ENSMUSG00000027748 Trpc4 transient receptor potential cation channel, subfamily C, member 4 protein_coding Mus_musculus

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