C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aryl hydrocarbon receptor nuclear translocator-like
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000133794 ARNTL 9606 + 11:13276652-13387266 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000389707 ARNTL-001 13277798-13387266 protein_coding
  ENST00000401424 ARNTL-003 13277798-13387266 protein_coding
  ENST00000403290 ARNTL-004 13277831-13387266 protein_coding
  ENST00000403482 ARNTL-005 13356878-13387266 protein_coding
  ENST00000403510 ARNTL-002 13277842-13387263 protein_coding
  ENST00000472842 ARNTL-006 13375679-13387263 retained_intron
  ENST00000480685 ARNTL-009 13277829-13356929 retained_intron
  ENST00000482049 ARNTL-008 13277885-13358558 protein_coding
  ENST00000485918 ARNTL-021 13349945-13354631 retained_intron
  ENST00000497429 ARNTL-007 13358434-13372409 processed_transcript
  ENST00000524392 ARNTL-014 13374093-13387266 nonsense_mediated_decay
  ENST00000527998 ARNTL-019 13277639-13358440 protein_coding
  ENST00000529050 ARNTL-016 13276652-13354377 protein_coding
  ENST00000529388 ARNTL-022 13277802-13360372 protein_coding
  ENST00000529390 ARNTL-013 13372209-13376771 retained_intron
  ENST00000529825 ARNTL-017 13277794-13358481 protein_coding
  ENST00000530357 ARNTL-018 13277815-13365592 protein_coding
  ENST00000531665 ARNTL-011 13309986-13357096 protein_coding
  ENST00000533520 ARNTL-020 13277793-13358514 protein_coding
  ENST00000534102 ARNTL-012 13365416-13369740 retained_intron
  ENST00000534544 ARNTL-015 13276652-13356777 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000389707ENST00000401424ENST00000403290ENST00000403482ENST00000403510ENST00000472842ENST00000497429ENST00000524392ENST00000529390ENST00000529825ENST00000531665ENST00000533520
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000389707 1.055±0.00 N/A N/A 1.520±0.06 N/A 2.675±0.00 N/A N/A 0.354±0.00 N/A N/A N/A 0.593±0.03 2.911±0.00
ENST00000401424 N/A N/A N/A 1.101±0.00 0.344±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000403290 N/A 1.365±0.00 N/A 3.167±0.00 0.589±0.00 0.563±0.00 N/A N/A 2.477±1.87 1.680±0.00 3.727±0.00 1.851±1.04 0.535±0.00 2.118±0.00
ENST00000403482 1.209±0.00 0.480±0.00 0.475±0.00 N/A 0.628±0.00 0.973±0.06 N/A 1.066±0.53 0.325±0.00 1.053±0.25 N/A 0.831±0.38 N/A 1.842±0.00
ENST00000403510 1.288±0.00 N/A N/A 1.719±0.00 N/A N/A 0.598±0.00 N/A 3.427±0.00 N/A N/A 1.140±0.00 0.456±0.15 N/A
ENST00000472842 N/A 0.428±0.00 N/A 0.890±0.00 0.183±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000497429 N/A N/A N/A N/A 0.975±0.00 N/A N/A N/A 1.068±0.00 N/A 0.732±0.00 N/A N/A N/A
ENST00000524392 N/A 1.043±0.00 N/A N/A 0.434±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000529390 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.169±0.00 2.405±0.00 12.198±0.00
ENST00000529825 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.069±0.00 N/A
ENST00000531665 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.476±0.00 N/A N/A N/A
ENST00000533520 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.183±0.00 2.362±0.00 12.096±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003PI CIL_0003PI_0001 CGP 11:13009577-13387266
CIL_0003PJ CIL_0003PJ_0001 CGP 11:13276652-13463297

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000060 IEA protein import into nucleus, translocation
GO:0000976 ISS transcription regulatory region sequence-specific DNA binding
GO:0000982 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0001046 IEA core promoter sequence-specific DNA binding
GO:0001047 ISS core promoter binding
GO:0001190 IEA RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006355 ISS:IEA regulation of transcription, DNA-templated
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007165 IEA signal transduction
GO:0007283 ISS spermatogenesis
GO:0007623 TAS circadian rhythm
GO:0016604 IEA nuclear body
GO:0017162 IPI aryl hydrocarbon receptor binding
GO:0032007 ISS negative regulation of TOR signaling
GO:0032922 ISS circadian regulation of gene expression
GO:0033391 ISS chromatoid body
GO:0042176 IEA regulation of protein catabolic process
GO:0042634 IMP regulation of hair cycle
GO:0042753 ISS positive regulation of circadian rhythm
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043425 IEA bHLH transcription factor binding
GO:0043565 ISS sequence-specific DNA binding
GO:0045599 ISS negative regulation of fat cell differentiation
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0050767 ISS regulation of neurogenesis
GO:0050796 ISS regulation of insulin secretion
GO:0051726 ISS regulation of cell cycle
GO:0051775 IDA response to redox state
GO:0051879 IDA Hsp90 protein binding
GO:0070888 IDA E-box binding
GO:0090263 ISS positive regulation of canonical Wnt signaling pathway
GO:0090403 ISS oxidative stress-induced premature senescence
GO:2000074 ISS regulation of type B pancreatic cell development
GO:2000323 ISS negative regulation of glucocorticoid receptor signaling pathway
GO:2000772 ISS regulation of cellular senescence
GO:2001016 ISS positive regulation of skeletal muscle cell differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006791 arntl1a aryl hydrocarbon receptor nuclear translocator-like 1a protein_coding Danio_rerio
ENSDARG00000035732 arntl1b aryl hydrocarbon receptor nuclear translocator-like 1b protein_coding Danio_rerio
ENSMUSG00000055116 Arntl aryl hydrocarbon receptor nuclear translocator-like protein_coding Mus_musculus

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