C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SRY (sex determining region Y)-box 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000134595 SOX3 9606 - X:140502987-140505503 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000370536 SOX3-001 140502987-140505503 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainHeartOvaryTestisENST00000370536
Transcript ID Adrenal Brain Heart Ovary Testis
ENST00000370536 0.013±0.00 0.181±0.16 0.026±0.00 0.766±0.71 1.829±0.22

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008R8 CIL_0008R8_0001 VISTA X:139949968-140551211
CIL_0001AO CIL_0001AO_0001 CGP X:139955725-140505503
CIL_0008YR CIL_0008YR_0001 VISTA X:139998751-140600034
CIL_000974 CIL_000974_0001 VISTA X:140211337-140812609
CIL_0008TQ CIL_0008TQ_0001 VISTA X:140292334-140893238
CIL_0007M2 CIL_0007M2_0001 UCNEbase X:140299081-140593102

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000979 ISS RNA polymerase II core promoter sequence-specific DNA binding
GO:0001106 ISS RNA polymerase II transcription corepressor activity
GO:0003677 TAS DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007417 TAS central nervous system development
GO:0007423 ISS sensory organ development
GO:0007530 IMP sex determination
GO:0009887 IEA organ morphogenesis
GO:0021854 ISS hypothalamus development
GO:0021983 ISS pituitary gland development
GO:0030900 IEA forebrain development
GO:0045665 ISS negative regulation of neuron differentiation
GO:0048515 IEA spermatid differentiation
GO:0048666 IEA neuron development
GO:0060009 IEA Sertoli cell development
GO:0060324 ISS face development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000053569 sox3 SRY-box containing gene 3 protein_coding Danio_rerio
ENSMUSG00000045179 Sox3 SRY (sex determining region Y)-box 3 protein_coding Mus_musculus

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