C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transient receptor potential cation channel, subfamily C, member 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137672 TRPC6 9606 - 11:101451564-101872562 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344327 TRPC6-001 101451564-101583928 protein_coding
  ENST00000348423 TRPC6-002 101452955-101583503 protein_coding
  ENST00000360497 TRPC6-003 101452955-101583503 protein_coding
  ENST00000526713 TRPC6-007 101504705-101872562 processed_transcript
  ENST00000527240 TRPC6-006 101491381-101504090 retained_intron
  ENST00000532133 TRPC6-004 101452872-101583506 protein_coding
  ENST00000532184 TRPC6-005 101453641-101455577 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000344327ENST00000348423ENST00000360497ENST00000527240ENST00000532133
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000344327 0.679±0.00 0.063±0.00 0.277±0.00 0.178±0.00 0.210±0.00 0.474±0.34 0.247±0.00 0.424±0.25 0.354±0.00 3.355±2.13 0.029±0.00 0.608±0.42 1.926±0.68 0.218±0.13
ENST00000348423 N/A N/A N/A 0.164±0.00 N/A N/A N/A 0.613±0.00 0.013±0.00 1.901±0.00 N/A 0.226±0.00 1.308±0.00 0.413±0.00
ENST00000360497 N/A N/A N/A N/A N/A N/A N/A N/A 0.570±0.00 2.854±0.00 N/A 0.515±0.00 1.462±0.00 0.303±0.00
ENST00000527240 N/A N/A N/A N/A N/A N/A N/A N/A 0.076±0.00 N/A N/A N/A N/A N/A
ENST00000532133 0.909±0.00 N/A 0.658±0.00 0.642±0.00 1.025±0.31 N/A 0.341±0.00 N/A N/A 2.485±0.57 N/A 1.528±0.00 0.927±0.00 0.266±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002C4 CIL_0002C4_0002 CGP 11:101451564-101916522

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005261 IEA cation channel activity
GO:0005262 IEA calcium channel activity
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005886 IDA plasma membrane
GO:0006811 IEA ion transport
GO:0006812 TAS cation transport
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007411 TAS axon guidance
GO:0007568 IEA aging
GO:0007596 TAS blood coagulation
GO:0015279 IEA store-operated calcium channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030168 TAS platelet activation
GO:0032414 IDA positive regulation of ion transmembrane transporter activity
GO:0034220 TAS ion transmembrane transport
GO:0036057 IEA slit diaphragm
GO:0051928 IDA positive regulation of calcium ion transport
GO:0055085 TAS:IEA transmembrane transport
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0070588 TAS calcium ion transmembrane transport
GO:0070679 IDA inositol 1,4,5 trisphosphate binding
GO:0071456 IEA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000056625 trpc6a transient receptor potential cation channel, subfamily C, member 6a protein_coding Danio_rerio
ENSDARG00000067730 trpc6b transient receptor potential cation channel, subfamily C, member 6b protein_coding Danio_rerio
ENSMUSG00000031997 Trpc6 transient receptor potential cation channel, subfamily C, member 6 protein_coding Mus_musculus

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