C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137872 SEMA6D 9606 + 15:47184101-47774223 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000316364 SEMA6D-004 47718489-47774223 protein_coding
  ENST00000354744 SEMA6D-005 47718489-47774223 protein_coding
  ENST00000355997 SEMA6D-201 47718489-47774222 protein_coding
  ENST00000358066 SEMA6D-006 47718489-47774223 protein_coding
  ENST00000389425 SEMA6D-003 47718461-47765480 protein_coding
  ENST00000389428 SEMA6D-007 47718489-47774223 protein_coding
  ENST00000536845 SEMA6D-002 47717363-47771933 protein_coding
  ENST00000537942 SEMA6D-202 47412390-47774220 protein_coding
  ENST00000558014 SEMA6D-001 47184101-47774221 protein_coding
  ENST00000558431 SEMA6D-014 47765822-47767303 retained_intron
  ENST00000558816 SEMA6D-008 47717457-47772882 protein_coding
  ENST00000559064 SEMA6D-015 47766577-47767515 protein_coding
  ENST00000559184 SEMA6D-009 47185663-47759864 protein_coding
  ENST00000559196 SEMA6D-013 47759723-47762319 protein_coding
  ENST00000560006 SEMA6D-016 47766580-47770765 protein_coding
  ENST00000560636 SEMA6D-010 47339067-47759802 protein_coding
  ENST00000561106 SEMA6D-011 47717402-47759983 retained_intron
  ENST00000561133 SEMA6D-012 47716998-47761428 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000316364ENST00000354744ENST00000358066ENST00000389425ENST00000389428ENST00000536845ENST00000537942ENST00000558014ENST00000558816ENST00000559064
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000316364 0.160±0.00 N/A N/A N/A 0.239±0.00 N/A 0.164±0.00 0.212±0.00 N/A N/A 0.315±0.00 2.260±1.67 1.607±0.89 0.180±0.00
ENST00000354744 0.769±0.00 N/A N/A 3.335±0.00 N/A 0.266±0.00 0.501±0.00 0.904±0.00 N/A 0.308±0.00 N/A N/A 1.607±0.00 0.540±0.00
ENST00000358066 N/A N/A N/A N/A N/A 0.176±0.00 N/A N/A N/A 1.119±0.00 N/A N/A N/A N/A
ENST00000389425 N/A N/A 2.006±0.00 N/A N/A N/A 0.531±0.00 N/A N/A 1.353±0.00 N/A N/A N/A N/A
ENST00000389428 N/A N/A 0.899±0.00 1.422±0.00 0.713±0.00 0.826±0.00 N/A 0.984±0.00 N/A N/A N/A N/A N/A N/A
ENST00000536845 N/A N/A 1.319±0.00 4.793±0.00 0.619±0.00 1.271±0.00 0.829±0.00 N/A 0.670±0.00 1.101±0.69 0.812±0.00 0.966±0.00 N/A N/A
ENST00000537942 N/A N/A N/A 0.870±0.00 N/A 0.212±0.00 N/A N/A 0.232±0.00 N/A N/A 1.787±0.00 1.066±0.00 N/A
ENST00000558014 N/A 0.300±0.00 N/A 0.875±0.00 0.299±0.00 0.168±0.00 N/A N/A 0.244±0.00 N/A N/A N/A N/A 0.271±0.00
ENST00000558816 N/A N/A N/A N/A 0.717±0.00 2.130±0.00 N/A 0.932±0.00 N/A 0.445±0.00 N/A N/A N/A N/A
ENST00000559064 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.777±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004NB CIL_0004NB_0001 CGP 15:47184101-48142672

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 IEA receptor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0007275 IEA multicellular organismal development
GO:0007411 TAS axon guidance
GO:0014911 IEA positive regulation of smooth muscle cell migration
GO:0014912 IEA negative regulation of smooth muscle cell migration
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0021591 IEA ventricular system development
GO:0030215 IEA semaphorin receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011533 sema6dl sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like protein_coding Danio_rerio
ENSMUSG00000027200 Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D protein_coding Mus_musculus

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