C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027200 Sema6d 10090 + 2:124089969-124667770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000051419 Sema6d-006 124610296-124665957 protein_coding
  ENSMUST00000076335 Sema6d-201 124610296-124667769 protein_coding
  ENSMUST00000077847 Sema6d-202 124610296-124667769 protein_coding
  ENSMUST00000078621 Sema6d-203 124610296-124667769 protein_coding
  ENSMUST00000103238 Sema6d-007 124653635-124665309 protein_coding
  ENSMUST00000103239 Sema6d-008 124610573-124667770 protein_coding
  ENSMUST00000103240 Sema6d-004 124610601-124665957 protein_coding
  ENSMUST00000103241 Sema6d-001 124089969-124667769 protein_coding
  ENSMUST00000132088 Sema6d-005 124610106-124662885 retained_intron
  ENSMUST00000137172 Sema6d-002 124089969-124143353 retained_intron
  ENSMUST00000151199 Sema6d-003 124143005-124507701 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076335ENSMUST00000077847ENSMUST00000078621ENSMUST00000103238ENSMUST00000103239ENSMUST00000103240ENSMUST00000103241ENSMUST00000132088
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076335 1.270±0.00 1.310±0.00 1.172±0.09 1.818±0.00 1.475±0.59 2.460±0.48 1.365±0.45 0.672±0.13 0.788±0.34 2.781±0.48 0.734±0.00 1.539±0.18 4.230±2.42 0.187±0.08
ENSMUST00000077847 1.950±0.00 N/A 1.179±0.14 2.408±1.03 0.924±0.10 N/A 1.965±0.00 0.638±0.27 0.771±0.11 2.036±0.00 0.792±0.42 0.916±0.00 1.368±0.30 0.215±0.00
ENSMUST00000078621 N/A N/A N/A 2.996±1.63 N/A N/A N/A 0.611±0.00 N/A N/A N/A N/A N/A N/A
ENSMUST00000103238 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.066±0.12 N/A 4.124±0.00 N/A
ENSMUST00000103239 4.444±1.46 3.190±0.69 1.526±0.02 4.101±2.44 3.688±1.53 6.301±1.66 2.562±0.79 1.139±0.28 1.603±0.52 14.828±4.24 0.690±0.10 4.373±2.13 2.868±1.09 0.190±0.01
ENSMUST00000103240 N/A 3.029±1.71 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.954±0.34 N/A N/A
ENSMUST00000103241 N/A N/A N/A 5.979±4.69 N/A N/A N/A N/A 0.618±0.01 N/A N/A N/A N/A N/A
ENSMUST00000132088 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.457±0.00 1.503±0.00 N/A 0.120±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004NB CIL_0004NB_0002 CGP 2:124089969-125088677

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004872 IEA receptor activity
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0014911 IDA positive regulation of smooth muscle cell migration
GO:0014912 IDA negative regulation of smooth muscle cell migration
GO:0016021 IEA integral component of membrane
GO:0021591 IDA ventricular system development
GO:0030154 IEA cell differentiation
GO:0030215 IPI semaphorin receptor binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011533 sema6dl sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, like protein_coding Danio_rerio
ENSG00000137872 SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D protein_coding Homo_sapiens

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