C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAP1, GTP-GDP dissociation stimulator 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138698 RAP1GDS1 9606 + 4:98261384-98443861 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264572 RAP1GDS1-004 98261431-98442117 protein_coding
  ENST00000339360 RAP1GDS1-006 98261518-98442334 protein_coding
  ENST00000380158 RAP1GDS1-002 98261417-98442373 protein_coding
  ENST00000408900 RAP1GDS1-005 98261518-98442334 protein_coding
  ENST00000408927 RAP1GDS1-001 98261453-98443861 protein_coding
  ENST00000453712 RAP1GDS1-007 98261469-98442666 protein_coding
  ENST00000503667 RAP1GDS1-009 98261396-98352567 nonsense_mediated_decay
  ENST00000503745 RAP1GDS1-019 98352513-98392080 processed_transcript
  ENST00000505378 RAP1GDS1-003 98261434-98392245 retained_intron
  ENST00000507303 RAP1GDS1-018 98261503-98392252 retained_intron
  ENST00000508213 RAP1GDS1-011 98261451-98392009 protein_coding
  ENST00000508490 RAP1GDS1-010 98261423-98352568 nonsense_mediated_decay
  ENST00000509011 RAP1GDS1-008 98261384-98392080 protein_coding
  ENST00000509501 RAP1GDS1-020 98379102-98421283 protein_coding
  ENST00000510870 RAP1GDS1-012 98261486-98391989 nonsense_mediated_decay
  ENST00000511212 RAP1GDS1-017 98261486-98392041 protein_coding
  ENST00000511379 RAP1GDS1-014 98261460-98379490 retained_intron
  ENST00000512857 RAP1GDS1-015 98261457-98391989 processed_transcript
  ENST00000514122 RAP1GDS1-016 98261461-98404586 protein_coding
  ENST00000514139 RAP1GDS1-021 98379159-98396909 protein_coding
  ENST00000515187 RAP1GDS1-013 98261479-98352588 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000339360ENST00000380158ENST00000408900ENST00000408927ENST00000453712ENST00000503745ENST00000509501ENST00000511379ENST00000514139
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000339360 N/A N/A N/A N/A 0.755±0.00 1.742±0.00 0.420±0.01 1.270±0.00 N/A N/A N/A 1.336±0.00 1.061±0.00 N/A
ENST00000380158 1.951±0.00 2.033±0.00 N/A 10.976±0.00 N/A 3.235±0.00 0.626±0.00 N/A N/A N/A N/A 2.812±0.00 N/A 2.898±0.00
ENST00000408900 1.531±0.00 N/A 3.856±0.00 11.282±0.00 2.206±0.39 2.340±0.00 N/A 1.932±0.00 2.185±0.00 3.834±0.00 0.437±0.00 N/A N/A N/A
ENST00000408927 3.953±0.00 5.114±0.00 N/A 3.170±0.00 0.794±0.13 1.674±0.06 0.718±0.00 3.542±0.00 1.327±0.14 N/A N/A 4.645±0.86 2.401±1.46 3.712±0.00
ENST00000453712 1.151±0.00 N/A N/A 11.819±0.00 1.081±0.00 1.817±0.00 1.088±0.00 4.210±0.00 1.900±0.00 2.765±0.35 0.463±0.02 N/A 1.485±0.19 5.255±0.29
ENST00000503745 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.355±0.00 N/A N/A N/A
ENST00000509501 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 20.216±0.00 15.492±0.00 31.955±0.00
ENST00000511379 N/A N/A N/A N/A 1.592±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000514139 N/A N/A N/A N/A N/A N/A 0.407±0.00 N/A 2.323±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005C0 CIL_0005C0_0002 CGP 4:98261384-98658629

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000221 IEA vacuolar proton-transporting V-type ATPase, V1 domain
GO:0005096 NAS GTPase activator activity
GO:0005488 IEA binding
GO:0005515 IEA protein binding
GO:0005739 IDA mitochondrion
GO:0005783 IDA endoplasmic reticulum
GO:0005829 IDA cytosol
GO:0014829 IEA vascular smooth muscle contraction
GO:0015991 IEA ATP hydrolysis coupled proton transport
GO:0031034 IEA myosin filament assembly
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032471 IMP negative regulation of endoplasmic reticulum calcium ion concentration
GO:0046961 IEA proton-transporting ATPase activity, rotational mechanism
GO:0051561 IMP positive regulation of mitochondrial calcium ion concentration
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073741 RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1 protein_coding Danio_rerio
ENSMUSG00000028149 Rap1gds1 RAP1, GTP-GDP dissociation stimulator 1 protein_coding Mus_musculus

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