C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WD repeat domain 61
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140395 WDR61 9606 - 15:78277835-78299794 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000267973 WDR61-001 78283235-78299794 protein_coding
  ENST00000558311 WDR61-006 78283235-78299605 protein_coding
  ENST00000558412 WDR61-012 78283235-78285900 retained_intron
  ENST00000558453 WDR61-014 78277835-78289637 protein_coding
  ENST00000558459 WDR61-017 78283256-78299591 protein_coding
  ENST00000558840 WDR61-007 78292632-78299636 processed_transcript
  ENST00000559332 WDR61-011 78283235-78286133 processed_transcript
  ENST00000559700 WDR61-003 78292074-78299609 retained_intron
  ENST00000559848 WDR61-010 78288339-78299597 nonsense_mediated_decay
  ENST00000559940 WDR61-005 78283235-78286863 retained_intron
  ENST00000560063 WDR61-004 78291762-78299607 retained_intron
  ENST00000560569 WDR61-016 78283468-78299570 protein_coding
  ENST00000560610 WDR61-009 78288289-78299601 nonsense_mediated_decay
  ENST00000560807 WDR61-013 78277835-78290029 protein_coding
  ENST00000560946 WDR61-008 78294475-78299614 retained_intron
  ENST00000561347 WDR61-002 78294737-78299703 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000267973ENST00000558459ENST00000559700ENST00000559848ENST00000559940ENST00000560063ENST00000560569ENST00000560610ENST00000561347
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000267973 3.543±0.00 5.698±0.00 N/A 6.414±4.73 6.381±4.14 2.882±0.34 6.051±0.00 11.068±0.00 2.931±0.00 3.052±0.00 N/A 12.180±8.06 13.256±6.63 10.879±0.00
ENST00000558459 4.093±0.00 6.131±0.00 1.681±0.00 N/A N/A 2.832±0.00 N/A 6.102±0.00 3.749±0.00 3.315±0.00 1.530±0.81 6.006±3.18 N/A 5.884±0.00
ENST00000559700 N/A N/A 1.524±0.00 N/A N/A N/A N/A N/A 2.555±0.00 1.848±0.00 0.683±0.00 N/A N/A N/A
ENST00000559848 N/A N/A 3.546±0.00 5.500±0.00 5.118±0.00 N/A N/A N/A N/A 4.062±0.00 0.932±0.00 1.814±0.00 N/A N/A
ENST00000559940 N/A N/A 0.359±0.00 0.682±0.00 N/A 0.568±0.00 N/A N/A 0.529±0.00 N/A 0.335±0.00 0.368±0.00 N/A N/A
ENST00000560063 N/A N/A N/A N/A N/A N/A N/A N/A 1.375±0.00 N/A N/A N/A N/A N/A
ENST00000560569 6.327±0.00 10.963±0.00 N/A 12.486±0.00 17.196±0.00 3.493±0.21 3.782±2.38 10.029±5.45 6.986±2.66 13.538±0.00 9.575±0.00 27.318±13.35 14.561±7.85 35.309±20.80
ENST00000560610 N/A N/A N/A N/A N/A N/A N/A 1.791±0.00 N/A N/A N/A N/A 8.679±0.00 24.587±0.00
ENST00000561347 N/A N/A N/A 1.158±0.00 N/A N/A N/A 1.250±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003TL CIL_0003TL_0001 CGP 15:78167468-78282196
CIL_0003TI CIL_0003TI_0001 CGP 15:78264086-78299794
CIL_00050O CIL_00050O_0002 CGP 15:78277835-78348230

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0016055 IEA Wnt signaling pathway
GO:0016593 IDA Cdc73/Paf1 complex
GO:0032968 IDA positive regulation of transcription elongation from RNA polymerase II promoter
GO:0035327 IDA transcriptionally active chromatin
GO:0045638 IDA negative regulation of myeloid cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051571 IMP positive regulation of histone H3-K4 methylation
GO:0055087 IDA Ski complex
GO:0080182 IMP histone H3-K4 trimethylation
GO:2001162 IMP positive regulation of histone H3-K79 methylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007755 wdr61 WD repeat domain 61 protein_coding Danio_rerio
ENSMUSG00000061559 Wdr61 WD repeat domain 61 protein_coding Mus_musculus

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