C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor coactivator 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140396 NCOA2 9606 - 8:70109762-70403805 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000452400 NCOA2-001 70109762-70403805 protein_coding
  ENST00000518287 NCOA2-002 70112070-70402079 nonsense_mediated_decay
  ENST00000518363 NCOA2-005 70113569-70148460 protein_coding
  ENST00000519724 NCOA2-004 70216696-70245375 protein_coding
  ENST00000520416 NCOA2-003 70216721-70402587 protein_coding
  ENST00000521239 NCOA2-007 70126609-70128747 retained_intron
  ENST00000522054 NCOA2-006 70137973-70141242 retained_intron
  ENST00000524223 NCOA2-008 70155971-70157146 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000452400ENST00000518287ENST00000518363
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000452400 2.433±0.00 1.212±0.00 3.812±0.20 2.283±0.08 3.386±0.84 2.767±1.36 2.285±0.46 2.669±1.32 2.669±1.54 0.955±0.00 2.944±1.61 1.511±0.18 3.713±0.00
ENST00000518287 N/A N/A N/A 1.183±0.00 N/A 1.041±0.00 N/A 1.476±0.00 N/A 1.071±0.00 N/A N/A N/A
ENST00000518363 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.403±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ME CIL_0007ME_0001 UCNEbase 8:70008937-70182178
CIL_0003BO CIL_0003BO_0001 CGP 8:70051651-70403805
CIL_0003BN CIL_0003BN_0001 CGP 8:70109762-70608387

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003682 IEA chromatin binding
GO:0003713 ISS:IEA transcription coactivator activity
GO:0004402 IEA histone acetyltransferase activity
GO:0004871 IEA signal transducer activity
GO:0005102 IEA receptor binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS:IEA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0008134 IEA transcription factor binding
GO:0010906 IEA regulation of glucose metabolic process
GO:0016573 IEA histone acetylation
GO:0016922 IPI ligand-dependent nuclear receptor binding
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375 IEA thyroid hormone receptor coactivator activity
GO:0035257 IPI:IEA nuclear hormone receptor binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:2000273 IEA positive regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017929 ncoa2 nuclear receptor coactivator 2 protein_coding Danio_rerio
ENSMUSG00000005886 Ncoa2 nuclear receptor coactivator 2 protein_coding Mus_musculus

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