C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor coactivator 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000005886 Ncoa2 10090 - 1:13139105-13374083 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000006037 Ncoa2-002 13142475-13374083 protein_coding
  ENSMUST00000068304 Ncoa2-201 13139159-13374083 protein_coding
  ENSMUST00000081713 Ncoa2-001 13139105-13372439 protein_coding
  ENSMUST00000124088 Ncoa2-005 13184606-13374029 retained_intron
  ENSMUST00000133232 Ncoa2-008 13148429-13151018 retained_intron
  ENSMUST00000139970 Ncoa2-006 13182284-13372429 retained_intron
  ENSMUST00000143603 Ncoa2-004 13165925-13374029 retained_intron
  ENSMUST00000145280 Ncoa2-007 13190106-13299722 protein_coding
  ENSMUST00000146784 Ncoa2-009 13146599-13148507 retained_intron
  ENSMUST00000147927 Ncoa2-003 13164501-13374083 retained_intron
  ENSMUST00000185275 Ncoa2-010 13145301-13146630 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000006037ENSMUST00000068304ENSMUST00000081713ENSMUST00000145280
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000006037 5.137±2.51 4.508±1.66 3.199±0.00 5.516±3.27 5.243±2.08 4.941±0.73 2.632±0.83 4.846±1.45 2.087±0.54 3.843±0.84 N/A 7.025±2.75 4.768±3.87 10.881±5.35
ENSMUST00000068304 2.588±1.21 3.486±1.08 2.045±0.00 3.786±1.91 2.681±1.09 3.615±1.84 2.441±1.09 3.617±1.68 2.310±1.61 5.799±0.18 1.183±0.23 3.798±1.89 4.107±1.64 3.738±0.98
ENSMUST00000081713 N/A 2.358±0.79 N/A N/A 1.025±0.00 2.042±0.45 0.849±0.01 1.441±0.36 N/A 1.866±0.11 0.305±0.06 3.115±0.07 1.122±0.00 2.280±0.00
ENSMUST00000145280 N/A N/A N/A 72.741±0.00 N/A N/A N/A N/A N/A N/A N/A 58.782±0.00 46.370±10.57 61.570±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ME CIL_0007ME_0002 UCNEbase 1:13097855-13197231
CIL_0003BO CIL_0003BO_0002 CGP 1:13113457-13374083
CIL_0003BN CIL_0003BN_0002 CGP 1:13139105-13589910

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003682 IDA chromatin binding
GO:0003713 IDA transcription coactivator activity
GO:0004402 IEA histone acetyltransferase activity
GO:0004871 IEA signal transducer activity
GO:0005102 IDA receptor binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0007165 IEA signal transduction
GO:0008134 IPI transcription factor binding
GO:0010906 IMP regulation of glucose metabolic process
GO:0016573 IEA histone acetylation
GO:0016922 IEA ligand-dependent nuclear receptor binding
GO:0030374 IDA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375 IDA thyroid hormone receptor coactivator activity
GO:0035257 IEA nuclear hormone receptor binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:2000273 IDA positive regulation of receptor activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017929 ncoa2 nuclear receptor coactivator 2 protein_coding Danio_rerio
ENSG00000140396 NCOA2 nuclear receptor coactivator 2 protein_coding Homo_sapiens

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