C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family, CARD domain containing 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000140853 NLRC5 9606 + 16:56989485-57083531 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262510 NLRC5-001 56989498-57083524 protein_coding
  ENST00000399221 NLRC5-026 57058065-57062003 protein_coding
  ENST00000436936 NLRC5-201 57017074-57083524 protein_coding
  ENST00000534927 NLRC5-029 57075925-57082597 retained_intron
  ENST00000534931 NLRC5-023 57045297-57055036 retained_intron
  ENST00000535284 NLRC5-024 57059183-57062004 retained_intron
  ENST00000535658 NLRC5-017 56989594-56991126 processed_transcript
  ENST00000536231 NLRC5-020 57026639-57030084 retained_intron
  ENST00000537056 NLRC5-012 57043581-57083524 nonsense_mediated_decay
  ENST00000538059 NLRC5-016 57004486-57020769 protein_coding
  ENST00000538110 NLRC5-006 57026423-57061933 protein_coding
  ENST00000538273 NLRC5-019 56989563-57021112 retained_intron
  ENST00000538453 NLRC5-009 57034172-57083531 nonsense_mediated_decay
  ENST00000538778 NLRC5-021 57041408-57061519 retained_intron
  ENST00000538805 NLRC5-004 57025687-57062003 protein_coding
  ENST00000538930 NLRC5-011 57041321-57062744 retained_intron
  ENST00000539144 NLRC5-013 57020713-57083519 protein_coding
  ENST00000539881 NLRC5-003 56989485-57048354 nonsense_mediated_decay
  ENST00000540182 NLRC5-010 57040688-57083524 nonsense_mediated_decay
  ENST00000541020 NLRC5-022 57041488-57043808 retained_intron
  ENST00000543030 NLRC5-008 57026879-57061966 protein_coding
  ENST00000543049 NLRC5-030 57080999-57082633 retained_intron
  ENST00000543103 NLRC5-014 57080819-57083520 retained_intron
  ENST00000543141 NLRC5-018 56989563-56992444 processed_transcript
  ENST00000543402 NLRC5-025 57059200-57061933 retained_intron
  ENST00000544189 NLRC5-027 57074171-57076851 retained_intron
  ENST00000544641 NLRC5-015 57003853-57020936 protein_coding
  ENST00000545081 NLRC5-007 57025762-57083519 nonsense_mediated_decay
  ENST00000545349 NLRC5-028 57069877-57077369 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262510ENST00000399221ENST00000436936ENST00000534927ENST00000536231ENST00000537056ENST00000538273ENST00000538453ENST00000538778ENST00000538805ENST00000539144ENST00000539881ENST00000543030ENST00000543103ENST00000543141ENST00000545081ENST00000545349
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262510 N/A N/A N/A 0.194±0.00 1.470±0.88 0.520±0.00 N/A N/A N/A 1.861±0.98 N/A 3.233±0.28 N/A N/A
ENST00000399221 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.660±0.00 N/A
ENST00000436936 1.477±0.00 N/A N/A 0.035±0.00 N/A N/A N/A 0.538±0.00 N/A 3.973±0.00 N/A 1.954±0.00 0.387±0.08 N/A
ENST00000534927 N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.338±0.00 N/A N/A N/A N/A
ENST00000536231 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.582±0.00 N/A N/A N/A
ENST00000537056 N/A 7.665±0.00 N/A N/A 1.152±0.00 N/A N/A 0.884±0.08 0.951±0.00 N/A N/A 2.193±0.00 0.847±0.00 N/A
ENST00000538273 N/A N/A N/A 0.412±0.00 N/A N/A N/A 2.417±0.00 N/A N/A N/A N/A N/A N/A
ENST00000538453 N/A N/A N/A N/A N/A N/A N/A 0.534±0.00 N/A N/A N/A N/A N/A N/A
ENST00000538778 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.487±0.00 N/A N/A N/A
ENST00000538805 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.107±0.00 N/A 0.306±0.00 N/A
ENST00000539144 1.991±0.00 7.157±0.00 N/A 0.508±0.00 0.922±0.00 0.319±0.00 1.024±0.00 0.697±0.00 N/A 5.044±0.00 N/A 1.085±0.00 0.212±0.00 0.513±0.00
ENST00000539881 N/A N/A 0.141±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000543030 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.241±0.00 N/A N/A N/A
ENST00000543103 N/A 11.480±0.00 N/A 0.195±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000543141 N/A N/A N/A N/A 5.687±0.00 N/A N/A N/A N/A 5.409±0.00 1.106±0.33 N/A N/A N/A
ENST00000545081 N/A N/A N/A N/A N/A 1.458±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000545349 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.747±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00051V CIL_00051V_0002 CGP 16:56961850-57083531
CIL_00051Y CIL_00051Y_0002 CGP 16:56989485-57148367

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032480 TAS negative regulation of type I interferon production
GO:0043549 IDA regulation of kinase activity
GO:0045087 IMP innate immune response
GO:0045345 IDA positive regulation of MHC class I biosynthetic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051607 IEP defense response to virus
GO:0060335 IDA positive regulation of interferon-gamma-mediated signaling pathway
GO:0060339 IDA negative regulation of type I interferon-mediated signaling pathway
GO:0060340 IDA positive regulation of type I interferon-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000024631 NLRC5 NLR family, CARD domain containing 5 protein_coding Danio_rerio
ENSMUSG00000074151 Nlrc5 NLR family, CARD domain containing 5 protein_coding Mus_musculus

Loading