C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: NLR family, CARD domain containing 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000539144 NLRC5-013 ENSG00000140853 9606 + 16:57020713-57083519 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLungOvaryPlacentaTestisENST00000539144
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000539144 1.991±0.00 7.157±0.00 0.508±0.00 0.922±0.00 0.319±0.00 1.024±0.00 0.697±0.00 5.044±0.00 1.085±0.00 0.212±0.00 0.513±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00051V CIL_00051V_0002 CGP 16:56961850-57083531
CIL_00051Y CIL_00051Y_0002 CGP 16:56989485-57148367

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0032088 IDA negative regulation of NF-kappaB transcription factor activity
GO:0032480 TAS negative regulation of type I interferon production
GO:0043549 IDA regulation of kinase activity
GO:0045087 IMP innate immune response
GO:0045345 IDA positive regulation of MHC class I biosynthetic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051607 IEP defense response to virus
GO:0060335 IDA positive regulation of interferon-gamma-mediated signaling pathway
GO:0060339 IDA negative regulation of type I interferon-mediated signaling pathway
GO:0060340 IDA positive regulation of type I interferon-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000053085 Nlrc5-003 protein_coding Mus_musculus 0 1469
ENSMUST00000182409 Nlrc5-004 retained_intron Mus_musculus 0 1243

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