C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: COP9 signalosome subunit 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141030 COPS3 9606 - 17:17246820-17281293 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000268717 COPS3-001 17246836-17281293 protein_coding
  ENST00000417352 COPS3-008 17260374-17281239 protein_coding
  ENST00000439936 COPS3-002 17246874-17280700 protein_coding
  ENST00000462236 COPS3-003 17264934-17281160 retained_intron
  ENST00000463097 COPS3-010 17248949-17255055 retained_intron
  ENST00000471414 COPS3-009 17254887-17260696 retained_intron
  ENST00000477299 COPS3-006 17262020-17281246 nonsense_mediated_decay
  ENST00000486032 COPS3-011 17246835-17247887 retained_intron
  ENST00000486810 COPS3-004 17260302-17276066 retained_intron
  ENST00000492672 COPS3-007 17261998-17281246 nonsense_mediated_decay
  ENST00000495640 COPS3-005 17264860-17270807 nonsense_mediated_decay
  ENST00000539941 COPS3-014 17246820-17280777 protein_coding
  ENST00000577210 COPS3-019 17260305-17281186 nonsense_mediated_decay
  ENST00000577246 COPS3-015 17262046-17281273 nonsense_mediated_decay
  ENST00000578317 COPS3-013 17246837-17281191 nonsense_mediated_decay
  ENST00000579716 COPS3-020 17246835-17249027 protein_coding
  ENST00000583160 COPS3-018 17261966-17270976 protein_coding
  ENST00000584216 COPS3-016 17260398-17281273 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000268717ENST00000439936ENST00000492672ENST00000539941ENST00000577210ENST00000578317ENST00000584216
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000268717 12.807±0.00 13.858±0.00 0.809±0.00 17.426±8.73 10.528±5.19 11.723±6.51 11.189±8.32 8.229±3.88 5.580±3.22 8.326±4.78 41.637±0.00 15.218±7.06 15.805±8.69 45.919±26.98
ENST00000439936 N/A N/A N/A N/A N/A N/A 1.178±0.00 N/A 2.103±0.00 N/A N/A 3.727±0.00 N/A N/A
ENST00000492672 N/A N/A 2.237±0.00 N/A N/A N/A N/A 2.946±0.00 N/A 2.802±0.00 7.590±0.00 N/A N/A N/A
ENST00000539941 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.375±0.00 7.827±0.00 N/A N/A N/A
ENST00000577210 N/A N/A N/A N/A N/A N/A N/A N/A 3.305±0.00 N/A N/A N/A N/A N/A
ENST00000578317 1.727±0.00 2.869±0.00 N/A N/A 1.983±0.00 N/A 1.193±0.00 N/A 1.084±0.00 N/A N/A N/A N/A N/A
ENST00000584216 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.945±0.00 43.993±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00040N CIL_00040N_0001 CGP 17:17212212-17281293
CIL_0009A0 CIL_0009A0_0001 VISTA 17:17235872-17840873
CIL_0000NX CIL_0000NX_0001 CGP 17:17246820-17347663

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IEA in utero embryonic development
GO:0005515 IPI:IEA protein binding
GO:0005737 IEA cytoplasm
GO:0007165 TAS signal transduction
GO:0008180 IDA COP9 signalosome
GO:0009416 TAS response to light stimulus
GO:0010388 IDA cullin deneddylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008623 cops3 COP9 constitutive photomorphogenic homolog subunit 3 protein_coding Danio_rerio
ENSMUSG00000019373 Cops3 COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana) protein_coding Mus_musculus

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