C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 4A3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141543 EIF4A3 9606 - 17:80135214-80147183 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000269349 EIF4A3-001 80135214-80147183 protein_coding
  ENST00000570625 EIF4A3-010 80135264-80136322 retained_intron
  ENST00000570837 EIF4A3-006 80139686-80140476 retained_intron
  ENST00000575668 EIF4A3-008 80136803-80138273 retained_intron
  ENST00000575957 EIF4A3-004 80141695-80147139 retained_intron
  ENST00000575978 EIF4A3-002 80135255-80139487 retained_intron
  ENST00000576547 EIF4A3-005 80140075-80147139 protein_coding
  ENST00000576573 EIF4A3-009 80135264-80137603 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000269349ENST00000575957ENST00000575978ENST00000576547ENST00000576573
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000269349 23.670±0.00 33.202±0.00 1.989±0.00 11.515±4.85 9.937±5.71 15.525±9.25 6.594±4.84 22.900±16.82 7.665±4.98 18.114±14.12 6.769±4.80 29.623±15.93 43.615±5.74 38.237±9.31
ENST00000575957 N/A N/A 1.589±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000575978 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.124±2.05 N/A N/A
ENST00000576547 N/A N/A N/A N/A N/A N/A 1.298±0.00 N/A N/A N/A N/A 34.443±0.00 40.032±0.00 44.431±0.00
ENST00000576573 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 15.701±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00005R CIL_00005R_0001 CGP 17:80101556-80147183
CIL_00031S CIL_00031S_0001 CGP 17:80135214-80209331

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 IMP nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000288 TAS nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
GO:0000289 TAS nuclear-transcribed mRNA poly(A) tail shortening
GO:0000398 IC mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0003729 IDA mRNA binding
GO:0004004 IDA ATP-dependent RNA helicase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006200 IEA ATP catabolic process
GO:0006364 IEA rRNA processing
GO:0008143 IDA poly(A) binding
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0017148 IDA negative regulation of translation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0035145 IDA exon-exon junction complex
GO:0044822 IDA poly(A) RNA binding
GO:0045727 IMP positive regulation of translation
GO:0048701 IMP embryonic cranial skeleton morphogenesis
GO:0051028 IEA mRNA transport
GO:0071013 IDA catalytic step 2 spliceosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014472 eif4a3 eukaryotic translation initiation factor 4A, isoform 3 protein_coding Danio_rerio
ENSMUSG00000025580 Eif4a3 eukaryotic translation initiation factor 4A3 protein_coding Mus_musculus

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