C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: regulatory associated protein of MTOR, complex 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000306801 RPTOR-001 ENSG00000141564 9606 + 17:80545268-80966368 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000306801
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000306801 2.393±0.00 3.603±0.00 1.188±0.00 4.882±0.00 1.828±0.63 0.933±0.64 2.948±0.00 1.254±0.27 1.387±0.38 1.648±0.49 2.690±0.00 2.283±0.57 3.218±1.26 3.494±0.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00042J CIL_00042J_0001 CGP 17:80467148-80966371
CIL_00042G CIL_00042G_0001 CGP 17:80544819-81009517

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001030 IDA RNA polymerase III type 1 promoter DNA binding
GO:0001031 IDA RNA polymerase III type 2 promoter DNA binding
GO:0001032 IDA RNA polymerase III type 3 promoter DNA binding
GO:0001156 IDA TFIIIC-class transcription factor binding
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005764 IDA lysosome
GO:0005765 IDA lysosomal membrane
GO:0005829 TAS cytosol
GO:0007050 TAS cell cycle arrest
GO:0008286 TAS insulin receptor signaling pathway
GO:0008361 IMP regulation of cell size
GO:0016049 IMP cell growth
GO:0019901 IPI protein kinase binding
GO:0030425 IEA dendrite
GO:0031669 IMP cellular response to nutrient levels
GO:0031929 IDA TOR signaling
GO:0031931 IDA TORC1 complex
GO:0032008 IDA positive regulation of TOR signaling
GO:0032403 IPI protein complex binding
GO:0042325 IEA regulation of phosphorylation
GO:0043025 IEA neuronal cell body
GO:0045945 IMP positive regulation of transcription from RNA polymerase III promoter
GO:0071230 IMP cellular response to amino acid stimulus
GO:0071889 IDA 14-3-3 protein binding
GO:0071902 IDA positive regulation of protein serine/threonine kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026671 Rptor-003 protein_coding Mus_musculus 0 4793
ENSMUST00000147781 Rptor-001 nonsense_mediated_decay Mus_musculus 0 3203
ENSMUST00000127899 Rptor-004 retained_intron Mus_musculus 0 2752
ENSMUST00000147772 Rptor-012 retained_intron Mus_musculus 0 2037
ENSMUST00000125583 Rptor-008 retained_intron Mus_musculus 0 1940
ENSMUST00000136662 Rptor-006 nonsense_mediated_decay Mus_musculus 0 1493
ENSMUST00000130049 Rptor-002 retained_intron Mus_musculus 0 1249
ENSMUST00000126802 Rptor-005 retained_intron Mus_musculus 0 1092
ENSMUST00000124401 Rptor-009 protein_coding Mus_musculus 0 414
ENSMUST00000131217 Rptor-011 nonsense_mediated_decay Mus_musculus 0 337
ENSMUST00000139728 Rptor-007 nonsense_mediated_decay Mus_musculus 0 278

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