C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: bromodomain containing 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000141867 BRD4 9606 - 19:15235519-15332545 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263377 BRD4-001 15235519-15280451 protein_coding
  ENST00000360016 BRD4-003 15252992-15332545 protein_coding
  ENST00000371835 BRD4-002 15247047-15280451 protein_coding
  ENST00000594066 BRD4-011 15244523-15246618 retained_intron
  ENST00000594841 BRD4-004 15256099-15331906 protein_coding
  ENST00000594842 BRD4-009 15256208-15257315 retained_intron
  ENST00000595926 BRD4-010 15253751-15255366 retained_intron
  ENST00000597315 BRD4-005 15265627-15332443 nonsense_mediated_decay
  ENST00000601071 BRD4-006 15267514-15272981 processed_transcript
  ENST00000601941 BRD4-008 15269013-15331907 protein_coding
  ENST00000602230 BRD4-007 15256135-15264400 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000263377ENST00000360016ENST00000371835ENST00000594841ENST00000597315ENST00000601071ENST00000601941
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000263377 6.727±0.00 N/A 0.769±0.00 N/A 0.470±0.00 N/A 0.766±0.00 N/A 0.390±0.00 N/A 0.545±0.00 10.887±5.83 10.163±0.00
ENST00000360016 N/A N/A N/A N/A N/A 0.151±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000371835 N/A N/A N/A 0.748±0.00 0.945±0.00 N/A 1.131±0.00 2.970±2.45 N/A 0.693±0.00 7.271±6.27 12.385±0.00 N/A
ENST00000594841 N/A 2.102±0.00 1.065±0.00 2.093±0.00 N/A 0.706±0.00 0.938±0.00 N/A N/A N/A N/A N/A N/A
ENST00000597315 N/A N/A N/A N/A N/A 0.667±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000601071 N/A N/A N/A N/A N/A N/A 5.981±0.00 N/A N/A N/A N/A N/A N/A
ENST00000601941 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.074±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DW CIL_0004DW_0002 CGP 19:15226919-15332545
CIL_00043N CIL_00043N_0001 CGP 19:15235519-15379798

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000083 IMP regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000790 IEA nuclear chromatin
GO:0000794 IDA condensed nuclear chromosome
GO:0001833 IEA inner cell mass cell proliferation
GO:0002039 IDA p53 binding
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005694 IDA chromosome
GO:0005737 IDA cytoplasm
GO:0006338 IDA chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0007059 IEA chromosome segregation
GO:0008024 IEA positive transcription elongation factor complex b
GO:0010971 IMP positive regulation of G2/M transition of mitotic cell cycle
GO:0016032 IEA viral process
GO:0032968 IMP positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043123 IDA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043388 IEA positive regulation of DNA binding
GO:0043983 IEA histone H4-K12 acetylation
GO:0044154 IEA histone H3-K14 acetylation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050727 IDA regulation of inflammatory response
GO:0070577 IDA lysine-acetylated histone binding
GO:1901407 IDA regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:2000002 IMP negative regulation of DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078904 brd4 bromodomain containing 4 protein_coding Danio_rerio
ENSMUSG00000024002 Brd4 bromodomain containing 4 protein_coding Mus_musculus

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