C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: bromodomain containing 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024002 Brd4 10090 - 17:32196274-32284722 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000003726 Brd4-201 32196276-32284097 protein_coding
  ENSMUST00000114475 Brd4-202 32206679-32284123 protein_coding
  ENSMUST00000119123 Brd4-004 32196274-32284097 protein_coding
  ENSMUST00000120276 Brd4-005 32204910-32284109 protein_coding
  ENSMUST00000121285 Brd4-003 32196274-32284109 protein_coding
  ENSMUST00000125899 Brd4-002 32213645-32284677 nonsense_mediated_decay
  ENSMUST00000127893 Brd4-001 32213610-32284722 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000003726ENSMUST00000114475ENSMUST00000119123ENSMUST00000120276ENSMUST00000121285ENSMUST00000127893
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000003726 2.355±0.00 1.502±0.11 N/A N/A 2.120±0.80 3.998±1.38 0.795±0.16 1.663±0.41 1.736±0.53 2.457±0.72 N/A 4.426±1.93 N/A 0.794±0.16
ENSMUST00000114475 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.705±0.00
ENSMUST00000119123 1.564±0.00 5.366±3.38 N/A N/A 2.061±1.38 2.792±1.17 N/A 1.134±0.00 N/A 3.528±0.04 N/A N/A N/A N/A
ENSMUST00000120276 2.138±0.48 N/A N/A N/A 1.415±0.00 N/A 1.130±0.16 2.124±0.00 1.728±0.62 N/A N/A N/A 4.897±2.09 0.955±0.07
ENSMUST00000121285 2.812±0.76 1.276±0.00 6.347±4.57 12.778±7.31 3.013±1.08 5.055±0.00 1.820±0.40 3.545±1.46 4.138±2.83 3.757±1.33 2.943±0.77 10.541±6.45 15.993±9.05 1.958±0.80
ENSMUST00000127893 N/A N/A N/A N/A N/A 6.648±1.66 N/A N/A N/A N/A N/A 7.306±1.48 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004DW CIL_0004DW_0003 CGP 17:32183770-32284722
CIL_00043N CIL_00043N_0002 CGP 17:32196274-32321153

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000083 IEA regulation of transcription involved in G1/S transition of mitotic cell cycle
GO:0000790 IDA nuclear chromatin
GO:0000794 IDA condensed nuclear chromosome
GO:0001833 IMP inner cell mass cell proliferation
GO:0002039 IEA p53 binding
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005694 IEA chromosome
GO:0005737 IEA cytoplasm
GO:0006338 IEA chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IPI protein phosphorylation
GO:0007059 IMP chromosome segregation
GO:0008024 IDA positive transcription elongation factor complex b
GO:0010971 IEA positive regulation of G2/M transition of mitotic cell cycle
GO:0032968 IEA positive regulation of transcription elongation from RNA polymerase II promoter
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043388 IDA positive regulation of DNA binding
GO:0043983 IMP histone H4-K12 acetylation
GO:0044154 IMP histone H3-K14 acetylation
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0050727 IEA regulation of inflammatory response
GO:0070577 IEA lysine-acetylated histone binding
GO:1901407 IEA regulation of phosphorylation of RNA polymerase II C-terminal domain
GO:2000002 IEA negative regulation of DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078904 brd4 bromodomain containing 4 protein_coding Danio_rerio
ENSG00000141867 BRD4 bromodomain containing 4 protein_coding Homo_sapiens

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