C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: coactivator-associated arginine methyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142453 CARM1 9606 + 19:10871513-10923070 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000327064 CARM1-002 10871513-10923070 protein_coding
  ENST00000344150 CARM1-003 10871703-10922721 protein_coding
  ENST00000586221 CARM1-001 10871828-10922777 nonsense_mediated_decay
  ENST00000586298 CARM1-010 10919929-10921900 protein_coding
  ENST00000586508 CARM1-006 10918986-10920870 retained_intron
  ENST00000588947 CARM1-008 10871596-10909136 protein_coding
  ENST00000589693 CARM1-005 10871910-10913931 nonsense_mediated_decay
  ENST00000590039 CARM1-009 10871853-10912252 nonsense_mediated_decay
  ENST00000590699 CARM1-004 10871673-10921771 nonsense_mediated_decay
  ENST00000592516 CARM1-007 10920667-10921934 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000327064ENST00000344150ENST00000586221ENST00000586298ENST00000586508ENST00000590699
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000327064 N/A N/A N/A N/A N/A N/A 0.197±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000344150 15.730±0.00 13.474±0.00 N/A N/A 6.435±4.62 1.965±0.00 0.609±0.00 1.066±0.00 3.878±3.00 1.055±0.00 1.602±0.00 13.311±8.67 19.050±6.64 23.163±0.00
ENST00000586221 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.760±0.00 N/A N/A N/A
ENST00000586298 N/A N/A N/A 7.012±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000586508 N/A N/A N/A N/A N/A N/A N/A 2.870±0.00 N/A N/A N/A N/A N/A N/A
ENST00000590699 N/A N/A 0.726±0.00 N/A N/A N/A N/A N/A N/A N/A 4.641±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002S5 CIL_0002S5_0001 CGP 19:10836575-10923070
CIL_0004ZT CIL_0004ZT_0002 CGP 19:10871513-10928681

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003420 IEA regulation of growth plate cartilage chondrocyte proliferation
GO:0003713 ISS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA:IEA cytoplasm
GO:0005829 ISS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006479 IEA protein methylation
GO:0008013 TAS beta-catenin binding
GO:0008152 IEA metabolic process
GO:0008168 IEA methyltransferase activity
GO:0008276 ISS:IEA protein methyltransferase activity
GO:0008284 IEA positive regulation of cell proliferation
GO:0008469 IBA histone-arginine N-methyltransferase activity
GO:0009405 IEA pathogenesis
GO:0016032 IEA viral process
GO:0016274 ISS protein-arginine N-methyltransferase activity
GO:0016571 ISS histone methylation
GO:0019919 IBA peptidyl-arginine methylation, to asymmetrical-dimethyl arginine
GO:0030374 ISS ligand-dependent nuclear receptor transcription coactivator activity
GO:0030518 IEA intracellular steroid hormone receptor signaling pathway
GO:0030520 IEA intracellular estrogen receptor signaling pathway
GO:0032091 IEA negative regulation of protein binding
GO:0033146 ISS regulation of intracellular estrogen receptor signaling pathway
GO:0034969 IEA histone arginine methylation
GO:0034970 IMP histone H3-R2 methylation
GO:0034971 ISS histone H3-R17 methylation
GO:0035242 ISS protein-arginine omega-N asymmetric methyltransferase activity
GO:0035246 IEA peptidyl-arginine N-methylation
GO:0035642 ISS histone methyltransferase activity (H3-R17 specific)
GO:0042054 IDA histone methyltransferase activity
GO:0042803 IEA protein homodimerization activity
GO:0044212 ISS transcription regulatory region DNA binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0045600 ISS positive regulation of fat cell differentiation
GO:0051591 IEA response to cAMP
GO:0060350 IEA endochondral bone morphogenesis
GO:0070577 ISS lysine-acetylated histone binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018698 carm1 coactivator-associated arginine methyltransferase 1 protein_coding Danio_rerio
ENSMUSG00000032185 Carm1 coactivator-associated arginine methyltransferase 1 protein_coding Mus_musculus

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