C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PR domain containing 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000142611 PRDM16 9606 + 1:3069168-3438621 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000270722 PRDM16-001 3069211-3438621 protein_coding
  ENST00000378389 PRDM16-005 3424919-3434095 processed_transcript
  ENST00000378391 PRDM16-003 3069197-3435421 protein_coding
  ENST00000463591 PRDM16-004 3244132-3386918 protein_coding
  ENST00000509860 PRDM16-002 3396491-3434293 protein_coding
  ENST00000511072 PRDM16-007 3069168-3434342 protein_coding
  ENST00000512462 PRDM16-009 3237931-3433925 processed_transcript
  ENST00000514189 PRDM16-008 3069211-3434342 protein_coding
  ENST00000606170 PRDM16-011 3425216-3426072 retained_intron
  ENST00000607632 PRDM16-010 3069183-3186591 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000270722ENST00000378389ENST00000378391ENST00000509860ENST00000511072ENST00000512462ENST00000514189ENST00000606170ENST00000607632
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000270722 N/A N/A N/A 0.339±0.26 0.020±0.00 0.325±0.00 0.784±0.71 1.200±0.00 0.021±0.01 N/A 0.113±0.00 0.315±0.08 0.108±0.01 N/A
ENST00000378389 N/A N/A N/A 0.491±0.00 0.040±0.00 N/A N/A N/A N/A N/A N/A 4.691±0.00 0.317±0.00 0.832±0.00
ENST00000378391 N/A N/A 0.345±0.00 0.054±0.00 N/A 0.102±0.06 N/A N/A N/A N/A 0.118±0.00 0.583±0.00 0.141±0.00 N/A
ENST00000509860 N/A N/A N/A N/A 0.012±0.00 N/A N/A N/A N/A N/A N/A 0.899±0.54 0.166±0.00 0.320±0.06
ENST00000511072 0.613±0.00 N/A N/A N/A 0.353±0.00 N/A 0.237±0.00 N/A N/A 0.138±0.00 N/A N/A N/A N/A
ENST00000512462 N/A N/A N/A N/A 0.009±0.00 N/A N/A N/A 0.053±0.00 N/A N/A N/A N/A N/A
ENST00000514189 N/A 0.345±0.00 N/A N/A N/A N/A N/A N/A 0.087±0.00 0.080±0.00 N/A N/A N/A N/A
ENST00000606170 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.378±0.00 N/A N/A N/A
ENST00000607632 N/A N/A 5.308±0.00 N/A N/A 0.497±0.00 1.637±0.00 N/A 0.359±0.00 1.097±0.00 N/A 4.677±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007XZ CIL_0007XZ_0001 VISTA 1:2589306-3193079
CIL_0007TB CIL_0007TB_0001 VISTA 1:2974017-3574864
CIL_00099V CIL_00099V_0001 VISTA 1:3045529-3649801

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003713 ISS transcription coactivator activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0017053 ISS transcriptional repressor complex
GO:0022008 IEA neurogenesis
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030853 IDA negative regulation of granulocyte differentiation
GO:0035019 IEA somatic stem cell maintenance
GO:0043457 ISS regulation of cellular respiration
GO:0043565 IDA sequence-specific DNA binding
GO:0043586 IEA tongue development
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046332 IEA SMAD binding
GO:0046872 IEA metal ion binding
GO:0050872 IEA white fat cell differentiation
GO:0050873 ISS brown fat cell differentiation
GO:0060021 IEA palate development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078324 prdm16 PR domain containing 16 protein_coding Danio_rerio
ENSMUSG00000039410 Prdm16 PR domain containing 16 protein_coding Mus_musculus

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