C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PR domain containing 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039410 Prdm16 10090 - 4:154316125-154636873 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030902 Prdm16-001 154316125-154636866 protein_coding
  ENSMUST00000070313 Prdm16-003 154316125-154636866 protein_coding
  ENSMUST00000097759 Prdm16-007 154316125-154636866 protein_coding
  ENSMUST00000105636 Prdm16-004 154316125-154636866 protein_coding
  ENSMUST00000105637 Prdm16-002 154316125-154636866 protein_coding
  ENSMUST00000105638 Prdm16-006 154316125-154636866 protein_coding
  ENSMUST00000124771 Prdm16-008 154355277-154636873 protein_coding
  ENSMUST00000131762 Prdm16-011 154346139-154348457 processed_transcript
  ENSMUST00000135064 Prdm16-010 154476469-154528765 processed_transcript
  ENSMUST00000141164 Prdm16-005 154316125-154636866 processed_transcript
  ENSMUST00000145217 Prdm16-013 154323331-154334852 processed_transcript
  ENSMUST00000149605 Prdm16-009 154476500-154636797 processed_transcript
  ENSMUST00000156069 Prdm16-012 154328260-154334922 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030902ENSMUST00000070313ENSMUST00000097759ENSMUST00000105636ENSMUST00000105637ENSMUST00000105638ENSMUST00000141164ENSMUST00000145217ENSMUST00000156069
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030902 0.207±0.00 N/A 0.216±0.00 0.302±0.13 N/A N/A N/A 0.749±0.00 N/A N/A N/A 0.206±0.00 0.010±0.00 0.134±0.00
ENSMUST00000070313 N/A 0.210±0.00 0.183±0.01 0.508±0.40 0.459±0.24 0.447±0.02 0.406±0.00 0.483±0.00 0.068±0.06 2.347±0.71 0.087±0.00 N/A 0.038±0.01 N/A
ENSMUST00000097759 N/A N/A N/A N/A N/A N/A N/A N/A 0.035±0.03 N/A 0.075±0.00 0.231±0.02 N/A N/A
ENSMUST00000105636 0.224±0.00 0.266±0.03 N/A 0.119±0.00 0.256±0.12 0.235±0.00 0.461±0.00 0.514±0.00 0.023±0.02 2.044±0.53 0.098±0.00 0.204±0.07 0.043±0.01 N/A
ENSMUST00000105637 N/A N/A N/A 0.510±0.00 N/A N/A N/A 0.640±0.19 0.042±0.00 N/A N/A 0.237±0.01 0.013±0.00 0.384±0.11
ENSMUST00000105638 N/A 0.303±0.07 N/A 0.697±0.00 0.191±0.01 0.409±0.00 N/A 0.380±0.07 0.077±0.00 1.037±0.00 0.069±0.00 0.129±0.00 N/A 0.422±0.30
ENSMUST00000141164 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.203±0.00 0.011±0.00 N/A
ENSMUST00000145217 N/A N/A N/A N/A N/A N/A N/A N/A 0.133±0.08 N/A N/A 2.301±0.52 1.276±0.83 3.725±0.00
ENSMUST00000156069 N/A N/A N/A N/A N/A 4.901±0.00 N/A N/A N/A N/A N/A 3.076±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099V CIL_00099V_0002 VISTA 4:154093365-154697126
CIL_0007TB CIL_0007TB_0002 VISTA 4:154156294-154757167

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0003676 IEA nucleic acid binding
GO:0003713 IDA transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0017053 IDA transcriptional repressor complex
GO:0022008 IDA neurogenesis
GO:0030512 ISS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030853 ISS negative regulation of granulocyte differentiation
GO:0035019 IDA somatic stem cell maintenance
GO:0043457 IDA regulation of cellular respiration
GO:0043565 IDA sequence-specific DNA binding
GO:0043586 IMP tongue development
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0046332 IPI SMAD binding
GO:0046872 IEA metal ion binding
GO:0050872 IDA white fat cell differentiation
GO:0050873 IMP brown fat cell differentiation
GO:0060021 IMP palate development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078324 prdm16 PR domain containing 16 protein_coding Danio_rerio
ENSG00000142611 PRDM16 PR domain containing 16 protein_coding Homo_sapiens

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