C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SET and MYND domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000143499 SMYD2 9606 + 1:214281102-214337131 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366957 SMYD2-001 214281233-214337131 protein_coding
  ENST00000415093 SMYD2-201 214281233-214336834 protein_coding
  ENST00000416415 SMYD2-006 214330977-214337131 protein_coding
  ENST00000460580 SMYD2-002 214281222-214337131 processed_transcript
  ENST00000471645 SMYD2-004 214281125-214337130 retained_intron
  ENST00000484459 SMYD2-005 214327494-214331070 processed_transcript
  ENST00000491455 SMYD2-003 214281102-214337131 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000366957ENST00000415093ENST00000460580ENST00000471645ENST00000484459ENST00000491455
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000366957 5.687±0.00 7.427±0.00 N/A 9.197±2.37 4.071±2.17 3.486±1.91 38.172±23.62 2.565±0.96 3.863±0.00 4.991±0.00 5.508±1.24 5.301±2.51 19.018±4.36 6.973±2.44
ENST00000415093 N/A N/A N/A N/A N/A N/A N/A 2.633±0.00 1.413±0.00 3.397±0.00 4.397±0.00 11.139±0.00 31.414±0.00 18.394±10.51
ENST00000460580 4.258±0.00 8.169±0.00 N/A 9.699±6.09 10.092±0.00 N/A 45.490±0.00 7.093±0.00 2.443±0.00 3.486±1.19 10.693±0.00 3.886±1.93 N/A 12.302±0.00
ENST00000471645 N/A N/A 0.774±0.00 N/A 1.283±0.00 0.330±0.00 2.559±0.00 0.615±0.05 0.370±0.00 N/A N/A 0.716±0.38 N/A N/A
ENST00000484459 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 9.839±0.00 N/A N/A N/A
ENST00000491455 N/A N/A N/A N/A N/A 1.302±0.00 N/A 0.380±0.00 N/A N/A 0.883±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089Q CIL_00089Q_0001 VISTA 1:213807252-214408737

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0000993 ISS RNA polymerase II core binding
GO:0002039 IPI p53 binding
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005829 ISS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0008285 ISS negative regulation of cell proliferation
GO:0010452 IEA histone H3-K36 methylation
GO:0016279 IDA protein-lysine N-methyltransferase activity
GO:0016571 IEA histone methylation
GO:0018026 IDA peptidyl-lysine monomethylation
GO:0018027 ISS peptidyl-lysine dimethylation
GO:0043516 IMP regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046872 IEA metal ion binding
GO:0046975 ISS histone methyltransferase activity (H3-K36 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055151 smyd2a SET and MYND domain containing 2a protein_coding Danio_rerio
ENSMUSG00000026603 Smyd2 SET and MYND domain containing 2 protein_coding Mus_musculus

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