C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SET and MYND domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026603 Smyd2 10090 - 1:189880492-189922363 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000027897 Smyd2-001 189880492-189922363 protein_coding
  ENSMUST00000130804 Smyd2-003 189880494-189889002 processed_transcript
  ENSMUST00000132289 Smyd2-004 189880642-189882372 retained_intron
  ENSMUST00000144452 Smyd2-002 189885046-189922253 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000027897ENSMUST00000130804ENSMUST00000132289
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000027897 20.877±4.70 26.029±1.43 24.740±4.94 30.439±20.19 20.456±6.30 11.780±2.66 31.004±5.69 11.549±0.69 11.282±3.50 7.629±0.72 121.196±7.86 32.947±8.51 35.454±16.14 6.995±1.11
ENSMUST00000130804 10.015±1.36 N/A 7.287±0.00 8.467±0.00 10.662±3.18 5.694±0.00 14.875±5.20 6.087±0.35 4.722±1.83 2.163±0.24 N/A 17.527±4.67 14.560±2.01 N/A
ENSMUST00000132289 N/A N/A N/A 45.438±0.00 N/A N/A N/A N/A N/A N/A N/A 40.760±0.00 59.537±13.00 11.211±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00089Q CIL_00089Q_0002 VISTA 1:189761322-190362331
CIL_0003Z6 CIL_0003Z6_0002 CGP 1:189880492-190170714

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000993 IDA RNA polymerase II core binding
GO:0002039 IEA p53 binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0008285 IDA negative regulation of cell proliferation
GO:0010452 IDA histone H3-K36 methylation
GO:0016279 ISS protein-lysine N-methyltransferase activity
GO:0016571 IDA histone methylation
GO:0018026 ISS peptidyl-lysine monomethylation
GO:0018027 IDA peptidyl-lysine dimethylation
GO:0043516 ISS regulation of DNA damage response, signal transduction by p53 class mediator
GO:0046872 IEA metal ion binding
GO:0046975 IDA histone methyltransferase activity (H3-K36 specific)

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055151 smyd2a SET and MYND domain containing 2a protein_coding Danio_rerio
ENSG00000143499 SMYD2 SET and MYND domain containing 2 protein_coding Homo_sapiens

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